AlphaFold_Prediction

Introduction to AlphaFold workflow

• Presentation

  • Introduction to AlphaFold2

  

• Specimen:

  • Human ion channel-like protein TACAN

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• Protocols included in the AlphaFold & Modelangelo modeling workflow

1. Import the sequence: Protocols 1a and 1b import the same sequence of TACAN protein. For details look at the Modeling tutorial and the protocol appendix

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2. Getting AlphaFold predictions: For details look at the Modeling tutorial and the protocol appendix

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2a. Downloading of AlphaFold prediction from AlphaFold Protein Structure Database: Monomer of HUMAN_TACAN protein.

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2b. AlphaFold prediction of the HUMAN_TACAN protein dimer using Google Colab and Chimera21 Jupiter notebook:

• NOTE: A Google account is needed

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• NOTE: The initial processing of AlphaFold predictions can be accomplished with specific Phenix protocols