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STARmap/RIBOmap analysis in Chowdhury et al.

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This repository contains scripts for the 'Brainstem neuropeptidergic neurons link a neurohumoral axis to satiation'.

  1. DRNSpatialSeq_1_Filtering.ipynb (single cell QC for STARmap/RIBOmap data)
  2. DRNSpatialSeq_2_PreprocessingAndIntegration.ipynb (preprocessing and data integration)
  3. DRNSpatialSeq_3_CellTyping.ipynb (cell clustering and visualization)

Other Info

Citation

Please cite our paper if you find our work useful:

Srikanta Chowdhury, Nachiket G. Kamatkar, Wendy Xueyi Wang, Christa A. Akerele, Jiahao Huang, Junlin Wu, Amajindi Nwankpa, Charlotte M. Kane, Varun M. Bhave, Hao Huang, Xiao Wang, Alexander R. Nectow, 2025. Brainstem neuropeptidergic neurons link a neurohumoral axis to satiation. Cell

Related Dataset

DOI

The related datasets can be found:

  1. Zenodo - Spatial sequencing dataset of the mouse DRN
  • Please use the most recent version of the dataset.

Contact

Contact us at wendyw@broadinstitute.org / jiahao@broadinstitute.org if you have any issues.

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Wendy (Xueyi) Wang, Jiahao Huang

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