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  • Currently, if the uniref db is indexed, the spire database will also be treated as an indexed db even if the index has not been generated (eg due to disk limits) which causes a crash.
  • This can be overcome by forcing MMSEQS_IGNORE_INDEX (eg SpireDB pairaln #775) but this will cause all dbs to be treated as not indexed which can sacrifice performance.

This is a small suggested change to support mixed (indexed/non-indexed) pairing databases.

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