To manually create a virtualenv on MacOS and Linux:
$ python -m venv .env
After the init process completes and the virtualenv is created, you can use the following step to activate your virtualenv.
$ source .env/bin/activate
If you are a Windows platform, you would activate the virtualenv like this:
% .env\Scripts\activate.bat
Once the virtualenv is activated, you can install the required dependencies.
$ pip install -r requirements.txt