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@open2c

Open Chromosome Collective

README.md

Welcome to Open2C!

Open2C is a community that develops and maintains open-source tools for 3D chromosome biology and genomic data science, primarily in Python.

Here's how to get started:

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  1. cooler Public

    A cool place to store your Hi-C

    Python 216 56

  2. cooltools Public

    The tools for your .cool's

    Jupyter Notebook 150 51

  3. pairtools Public

    Extract 3D contacts (.pairs) from sequencing alignments

    Python 112 33

  4. bioframe Public

    Genomic interval operations on Pandas DataFrames

    Python 183 36

  5. distiller-nf Public

    A modular Hi-C mapping pipeline

    Groovy 94 25

  6. polychrom Public

    Chromosome polymer simulations and in silico capture experiments

    Python 48 16

Repositories

Showing 10 of 28 repositories
  • distiller-sm Public

    a Snakemake version of distiller - the Open2C Hi-C mapping workflow

    Python 4 MIT 3 8 0 Updated May 1, 2025
  • bioframe Public

    Genomic interval operations on Pandas DataFrames

    Python 183 MIT 36 29 5 Updated Apr 28, 2025
  • cooler Public

    A cool place to store your Hi-C

    Python 216 BSD-3-Clause 56 37 (1 issue needs help) 8 Updated Apr 28, 2025
  • polychrom Public

    Chromosome polymer simulations and in silico capture experiments

    Python 48 MIT 16 9 (1 issue needs help) 0 Updated Apr 16, 2025
  • polykit Public
    Python 6 MIT 3 1 0 Updated Apr 16, 2025
  • .github Public
    0 MIT 0 0 0 Updated Feb 10, 2025
  • looplib Public

    A library to analyse the structure of 1d loops and simulate loop extrusion by loop extruding factors.

    Cython 10 6 3 3 Updated Feb 10, 2025
  • pairtools Public

    Extract 3D contacts (.pairs) from sequencing alignments

    Python 112 MIT 33 43 (2 issues need help) 7 Updated Jan 31, 2025
  • polychrom-hoomd Public
    Python 7 MIT 4 0 0 Updated Jan 29, 2025
  • open2c.github.io Public

    Welcome to the Open Chromosome Collective!

    Ruby 2 2 0 0 Updated Jan 20, 2025
View all repositories

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