Add Parabricks DeepVariant module #724
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PR checklist
nf-core pipelines lint
).nextflow run . -profile test,docker --outdir <OUTDIR>
).nextflow run . -profile test_singleton,docker --outdir <OUTDIR>
).nextflow run . -profile debug,test,docker --outdir <OUTDIR>
).docs/usage.md
is updated.docs/output.md
is updated.CHANGELOG.md
is updated.README.md
is updated (including new tool citations and authors/contributors).Description
This PR adds the
parabricks/deepvariant
module for GPU-accelerated variant calling in thenf-core/raredisease
pipeline.At the Clinical Institute of Special Laboratory Diagnostics, University Medical Centre Ljubljana, we have been using this implementation internally, as it significantly accelerates variant calling without introducing major differences in benchmark results compared to the CPU-based DeepVariant implementation.
We are contributing this module so that:
Tests performed
We successfully ran the following tests:
We are happy to receive feedback on how this contribution can be better integrated and aligned with nf-core standards, as well as any recommendations for improving its adoption and usability across the wider community.