opc_analysis

Janes Lab - mouse glioma analysis

Code for publication:

Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis Matthew D Sutcliffe, Rui P Galvao, Lixin Wang, Jungeun Kim, Lauren K Rosenfeld, Shambhavi Singh, Hui Zong, Kevin A Janes

https://pubmed.ncbi.nlm.nih.gov/33531372/

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Top-level folder is the expected working directory for all scripts/functions.

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These scripts expect folders (not included) titled:

1. build -> .RData files that include intermediate variables. Generated because running some of the files takes a nontrivial amount of time.
2. data -> raw data files that include RSEM CSVs, overdispersion simulation results, etc.
3. external -> contains downloaded data from external sources and publications
4. plots -> contains generated PDF files of figure panels