This repository contains the R scripts and metadata used to reproduce main figures in the following preprint:
Allostery is a widespread cause of loss-of-function variant pathogenicity (bioRxiv, 2025)
Raw and processed datasets for the human proteome-wide analysis can be accessed from the associated Zenodo records:
🧑🔧 For any feedback or requests, please get in touch via pull requests or via email: xl7@sanger.ac.uk.