Psaila-Wang.Molecular Cell.2020

This repository linked with Psaila B*,#, Wang G#, Rodriguez-Meira A,...Thongjuea S*, Mead A* et al. Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets[J]. Molecular cell, 2020, 78(3): 477-492. e8.

'#' equal contribution

'*' corresponding authors

Full paper: https://www.sciencedirect.com/science/article/pii/S1097276520302343

R objects can be downloaded using the following links:

1. All aggregates (MF patients + Healthy donors) http://sara.molbiol.ox.ac.uk/public/gwang/Psaila_Wang_MC2020/All.rdata

2. MF aggregates (MF patients only) http://sara.molbiol.ox.ac.uk/public/gwang/Psaila_Wang_MC2020/MF.rdata

3. Control aggregates (Healthy donors only) http://sara.molbiol.ox.ac.uk/public/gwang/Psaila_Wang_MC2020/HD.rdata

4. MKP clusters (linked to Fig5, extracted MKP cells + AUcell) http://sara.molbiol.ox.ac.uk/public/gwang/Psaila_Wang_MC2020/MKP.rdata

You can find the codes for each Figure code folder above. Lineage genes can be found in the .gmt file above.

A shiny app with data was built.

You can reach by https://github.com/supatt-lab/SingCellaR-myelofibrosis