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Move VEP files from a 110 path to GRCh38. #844

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Merged
merged 1 commit into from
Jul 24, 2024
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@bpblanken bpblanken commented Jul 24, 2024

In preparation for supporting GRCh37 on VEP 11190. This is cleaner anyways:

bblanken@wmbbe-67c seqr-loading-pipelines % gsutil ls gs://seqr-reference-data/vep/GRCh38/
gs://seqr-reference-data/vep/GRCh38/AlphaMissense_hg38.tsv.gz
gs://seqr-reference-data/vep/GRCh38/AlphaMissense_hg38.tsv.gz.tbi
gs://seqr-reference-data/vep/GRCh38/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz
gs://seqr-reference-data/vep/GRCh38/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz.fai
gs://seqr-reference-data/vep/GRCh38/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz.gzi
gs://seqr-reference-data/vep/GRCh38/homo_sapiens_vep_110_GRCh38.tar.gz
gs://seqr-reference-data/vep/GRCh38/uORF_5UTR_GRCh38_PUBLIC.txt
gs://seqr-reference-data/vep/GRCh38/vep-GRCh38.json

@bpblanken bpblanken requested a review from a team as a code owner July 24, 2024 00:26
@@ -12,7 +12,7 @@ export PROJECT="$(gcloud config get-value project)"
export VEP_CONFIG_PATH="$(/usr/share/google/get_metadata_value attributes/VEP_CONFIG_PATH)"
export VEP_REPLICATE="$(/usr/share/google/get_metadata_value attributes/VEP_REPLICATE)"
export ASSEMBLY=GRCh38
export VEP_DOCKER_IMAGE=gcr.io/seqr-project/vep-docker-image:110
export VEP_DOCKER_IMAGE=gcr.io/seqr-project/vep-docker-image:GRCh38
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bblanken@wmbbe-67c seqr-loading-pipelines % docker pull gcr.io/seqr-project/vep-docker-image:GRCh38
GRCh38: Pulling from seqr-project/vep-docker-image
Digest: sha256:bc2dc75c1016f9cba2d39c91fcfd4c4f2098634f0b5585e2b0a0c7f8d069b4a8
Status: Image is up to date for gcr.io/seqr-project/vep-docker-image:GRCh38
gcr.io/seqr-project/vep-docker-image:GRCh38

also there.

@bpblanken bpblanken merged commit f7992eb into dev Jul 24, 2024
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bpblanken added a commit that referenced this pull request Jul 25, 2024
* Move vep files (#844)

* Add mito local constraint (#845)

* Add mito local constraint

* Fix tests

* lint
bpblanken added a commit that referenced this pull request Aug 2, 2024
* Move vep files (#844)

* Add mito local constraint (#845)

* Add mito local constraint

* Fix tests

* lint

* Benb/migration task (#834)

* split import and validate

* lint and share function

* ruff

* change dep

* tweak update

* lint

* wrong method

* correct method

* mocks

* change sample type annotation on test

* hack on migration

* sort return list

* move the migration

* still hacking

* better!

* getting there

* Cleaner

* ruff

* Finish it off

* migration

* rename var

* add migrations to annotations table

* fix test import

* actually fix the test

* add migrations

* not used here

* use globals

* missed one

* a hilarious typo

* Update migrate_variant_annotations_table.py

* correct sign

* add lookup migration

* Add lookup table migration

* adjust migration

* ruff

* Add to tasks

* ensure a migration cannot run before a previous migration!

* ruff

* fix bug

* lint

* add referencegenomedatasetype

* Annoying but fixed

* Add new SV annotations for VCF export. (#857)

* Add SV annotations

* ruff

* push

* ruff

* Update update_variant_annotations_table_with_new_samples_test.py

* Add a task to export the SV annotations table to VCF. (#858)

* Export VCF task

* Fix test

* lint

* Resolve the assumption in the pipeline that remap/pedigree files are immutable. (#856)

* add remap_pedigree hash

* add func

* all the imports

* ruff

* Fix it

* support missing remap

* ruff

* ruff

* ruff

* tweak the type

* tweak the type

* Fix test

* ruff

* add remap pedigree hash

* Explicit int32

* lint

* Update io.py

* ruff

* lint

* hash

* Flappy test

* wrong pedigree

* bad colon

* finish tests

* add a test

* add pedigree

* Fix test
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2 participants