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@Gottwein-Lab

Gottwein Lab

Repository for code created by/for the Gottwein Lab at Northwestern University.

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  1. DepMap_Mining DepMap_Mining Public

    Code for identifying cohort-specific oncogenic dependencies and cohort-insensitive pan-essentials using DepMap + a cohort of CRISPR screens analyzed with MAGeCk.

    Jupyter Notebook 1 2

  2. 2022_cFLIP_Stats_Figures 2022_cFLIP_Stats_Figures Public

    Code and workbooks for figures and statistical testing from 2022 manuscript in preparation.

    Jupyter Notebook

  3. Gottwein_CRISPR_Variant_Calling Gottwein_CRISPR_Variant_Calling Public

    Script for characterizing and quantiftying variants based on data returned from the Massachusetts General Hospital CCIB DNA Core.

    Python

  4. CRISPR_Screen_Processing CRISPR_Screen_Processing Public

    Forked from nkuehnle/CRISPR_Screen_Processing

    A basic working example that you can follow through to semi-automate the analysis of pooled CRISPR screen data in a uniform way using MAGeCK and/or DrugZ for enrichment/depletion analysis. See Read…

    Shell

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