Anthropomorphic Fx

Body Mass Index (BMI)

Function

• Rx_BMI(Height,Weight,[Metric])

Equation

• BMI = (Weight in kg) / (Height in m)²

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Weight	Number	Yes	Weight in kilograms or pounds.
Metric	Boolean	No	Measurement units of height and weight. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	BMI in kg/m2.

Interpretation

BMI	Weight Status
Below 18.5	Underweight
18.5-24.9	Normal or Healthy Weight
25.0-29.9	Overweight
30.0 and Above	Obese

References

• Keys A, Fidanza F, Karvonen MJ, et al. Indices of relative weight and obesity. J Chronic Dis. 1972;25:329-43.
• Centers for Disease Control and Prevention (CDC)

Body Surface Area (BSA)

Functions

• Rx_BSA_DuBois(Height,Weight,[Metric])
• Rx_BSA_Mosteller(Height,Weight,[Metric])

Equations

Name	Equation
Du Bois	BSA = 0.007184 * (Weight in kg)0.425 * (Height in cm)0.725
Mosteller	BSA = [(Height in cm) * (Weight in kg)]0.5 / 60

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Weight	Number	Yes	Weight in kilograms or pounds.
Metric	Boolean	No	Measurement units of height and weight. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	BSA in m2.

References

• Du Bois D, Du Bois EF. Clinical calorimetry. Tenth paper. A formula to estimate the approximate surface area if height and weight be known. Arch Intern Med. 1916;17:863.
• Mosteller RD. Simplified calculation of body-surface area. N Engl J Med. 1987;317:1098.

Ideal Body Weight (IBW)

Function

• Rx_IBW_Devine(Height,Female,[Metric])

Equations

Name	Equation
Devine (Male)	IBW = 50kg + 2.3kg * [(Height in inches) - 60]
Devine (Female)	IBW = 45.5kg + 2.3kg * [(Height in inches) - 60]
Hamwi (Male)	IBW = 106lbs + 6lbs * [(Height in inches) - 60]
Hamwi (Female)	IBW = 100lbs + 5lbs * [(Height in inches) - 60]
Miller (Male)	IBW = 56.2kg + 1.41kg * [(Height in inches) - 60]
Miller (Female)	IBW = 53.1kg + 1.36kg * [(Height in inches) - 60]
Robinson (Male)	IBW = 52kg + 1.9kg * [(Height in inches) - 60]
Robinson (Female)	IBW = 49kg + 1.7kg * [(Height in inches) - 60]

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Female	Boolean	Yes	Sex. [True=Female; False=Male]
Metric	Boolean	No	Measurement units of height. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	IBW in kilograms.

References

• Devine BJ. Case number 25: Gentamicin therapy. Drug Intell Clin Pharm. 1974;8:650-5.
• Hamwi GJ. Therapy: changing dietary concepts. New York: American Diabetes Association; 1964.
• Miller DR, Carlson JD, Lloyd BJ, Day BJ. Determining ideal body weight (and mass). Am J Hosp Pharm. 1983;40:1622–5.
• Robinson JD, Lupkiewicz SM, Palenik L, Lopez LM, Ariet M. Determination of ideal body weight for drug dosage calculations. Am J Hosp Pharm. 1983;40:1016–9.

Adjusted Body Weight (AdjBW)

Function

• Rx_AdjBW_Devine(Height,Weight,Female,[Metric])

Equation

• AdjBW = IBW + 0.4 * (Actual Body Weight - IBW)

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Weight	Number	Yes	Weight in kilograms or pounds.
Female	Boolean	Yes	Sex. [True=Female; False=Male]
Metric	Boolean	No	Measurement units of height and weight. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	AdjBW in kilograms.

Notes

• Only use in obese patients (if a patient’s actual weight is greater than 20-30% of his or her ideal body weight)

References

• Blouin RA, Mann HJ, Griffen WO, et al. Tobramycin pharmacokinetics in morbidly obese patients. Clin Pharmacol Ther. 1979;26:508-12.
• Bauer LA, Blouin RA, Griffen WO, et al. Amikacin pharmacokinetics in morbidly obese patients. Am J Hosp Pharm. 1980;37:519-22
• Bauer LA, Edwards WA, Dellinger EP, et al. Influence of weight on aminoglycoside pharmacokinetics in normal weight and morbidly obese patients. Eur J Clin Pharmacol. 1983;24:643-7.

Lean Body Weight (LBW)

Function

• Rx_LBW(Height,Weight,Female,[Metric])

Equations

Name	Equation
LBW (Male)	LBW = [9270 * (Weight in kg)] / [6680 + (216 * BMI)]
LBW (Female)	LBW = [9270 * (Weight in kg)] / [8780 + (244 * BMI)]

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Weight	Number	Yes	Weight in kilograms or pounds.
Female	Boolean	Yes	Sex. [True=Female; False=Male]
Metric	Boolean	No	Measurement units of height and weight. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	LBW in kilograms.

Notes

• Only use in obese patients (if a patient’s actual weight is greater than 20-30% of his or her ideal body weight)

References

• Janmahasatian S, Duffull SB, Ash S, et al. Quantification of lean body weight. Clin Pharmacokinet. 2000;39:215-31.

Ideal Body Weight (IBW) Under 60 Inches

Functions

• Rx_IBW_Baseline(Height,Female,[Metric])
• Rx_IBW_BMI(Height,Female,[Metric])
• Rx_IBW_Hume(Height,Weight,Female,[Metric])

Equations

Name	Equation
Baseline (Male)	IBW = 50kg - 0.833kg for each inch below 60 inches
Baseline (Female)	IBW = 45.5kg - 0.758kg for each inch below 60 inches
BMI (Male)	IBW = 50 * [(Height in cm) / 152.4]2
BMI (Female)	IBW = 45.5 * [(Height in cm) / 152.4]2
Hume (Male)	IBW = [0.3281 * (Weight in kg)] + [0.33939 * (Height in cm)] - 29.5336
Hume (Female)	IBW = [0.29569 * (Weight in kg)] + [0.41813 * (Height in cm)] - 43.2933

Parameters

Name	Type	Required	Notes
Height	String	Yes	Height in centimeters or inches. Height in inches may be formatted as 5'10".
Weight	Number	Yes	Weight in kilograms or pounds.
Female	Boolean	Yes	Sex. [True=Female; False=Male]
Metric	Boolean	No	Measurement units of height and weight. [True=Metric (Default); False=US]

Returns

Type	Notes
Number	IBW in kilograms.