Introduction

[Work in progress]

SIRIUS (Systematische Identifikation Redundanter, Identisch Uebersetzter Sequenzen) is a synthetic biology tool leveraging Google OR-Tools mixed-integer programming to design genetic sequences with the shortest and fewest possible homologous fragments between pairs within minutes.

• Design n gene sequences all translating to a given protein P
• Synthesize sequences with maximal, optimal divergence
• Extremely fast and computationally efficient
• Written in pure C++

Documentation

You may find the documentation for SIRIUS at its GitHub Wiki.

Support

If you run into any issues or have suggestions for SIRIUS, please report them on our GitHub Issues tracker. It's the fastest way to get support and helps us improve SIRIUS for everyone. You may also email the authors at their provided e-mail addresses on the publication directly.

About

SIRIUS has been developed and is maintained by Amirsadra Mohseni, and Stefano Lonardi at the University of California, Riverside.