diff --git a/boards/st/nucleo_c071rb/nucleo_c071rb.dts b/boards/st/nucleo_c071rb/nucleo_c071rb.dts
index 53f72085ba595..c6faae2b770dd 100644
--- a/boards/st/nucleo_c071rb/nucleo_c071rb.dts
+++ b/boards/st/nucleo_c071rb/nucleo_c071rb.dts
@@ -78,6 +78,11 @@
 	status = "okay";
 };
 
+&clk_hsi48 {
+	status = "okay";
+	crs-usb-sof;
+};
+
 &rcc {
 	clocks = <&clk_hse>;
 	clock-frequency = <DT_FREQ_M(48)>;
diff --git a/dts/arm/st/c0/stm32c071.dtsi b/dts/arm/st/c0/stm32c071.dtsi
index 00cbbb6a118a8..6e4ea66b788a0 100644
--- a/dts/arm/st/c0/stm32c071.dtsi
+++ b/dts/arm/st/c0/stm32c071.dtsi
@@ -7,6 +7,15 @@
 #include <st/c0/stm32c031.dtsi>
 
 / {
+	clocks {
+		clk_hsi48: clk-hsi48 {
+			#clock-cells = <0>;
+			compatible = "st,stm32-hsi48-clock";
+			clock-frequency = <DT_FREQ_M(48)>;
+			status = "disabled";
+		};
+	};
+
 	soc {
 		compatible = "st,stm32c071", "st,stm32c0", "simple-bus";
 
diff --git a/include/zephyr/dt-bindings/clock/stm32c0_clock.h b/include/zephyr/dt-bindings/clock/stm32c0_clock.h
index 2489c48f1e933..e76ac3d819013 100644
--- a/include/zephyr/dt-bindings/clock/stm32c0_clock.h
+++ b/include/zephyr/dt-bindings/clock/stm32c0_clock.h
@@ -24,8 +24,11 @@
 /* defined in stm32_common_clocks.h */
 /** Fixed clocks  */
 /* Low speed clocks defined in stm32_common_clocks.h */
+/* STM32_SRC_HSI relates to HSI48 clock mentioned in RM0490 Reference Manual */
 #define STM32_SRC_HSI		(STM32_SRC_LSI + 1)
-#define STM32_SRC_HSE		(STM32_SRC_HSI + 1)
+/* STM32_SRC_HSI48 relates to HSIUSB48 mentioned in RM0490 Reference Manual */
+#define STM32_SRC_HSI48		(STM32_SRC_HSI + 1)
+#define STM32_SRC_HSE		(STM32_SRC_HSI48 + 1)
 /** Peripheral bus clock */
 #define STM32_SRC_PCLK		(STM32_SRC_HSE + 1)