Issue while calculating moholanobish distance step

[UpalabdhaD]

i am running the pipeline, currently while operating on step 9 with example dataset provided got the following error.

• OS: debian 12

• python version: 2.7.18

• script for step 09:

'{bash}

#!/bin/bash

main_dir="/home/upalabdha/Documents/02_work_collabs/KS/Prj_BatGenome/hcoErosions-master"

python generate_md_values.py
-reference hg38
-speciesList $main_dir/species.txt
-geneTranscriptIds $main_dir/ref_genes/hg38_clean.all.genes_id
'

• command:

bash s09_moholanobishDistance.sh

• Error:

135942
Traceback (most recent call last):
File "generate_md_values.py", line 129, in
d = get_species_md_dict (r, query, transcript_gene_dict)
File "generate_md_values.py", line 80, in get_species_md_dict
C_inv = np.linalg.inv(C)
File "/home/upalabdha/mambaforge/envs/hcoErosions_env/lib/python2.7/site-packages/numpy/linalg/linalg.py", line 551, in inv
ainv = _umath_linalg.inv(a, signature=signature, extobj=extobj)
File "/home/upalabdha/mambaforge/envs/hcoErosions_env/lib/python2.7/site-packages/numpy/linalg/linalg.py", line 97, in _raise_linalgerror_singular
raise LinAlgError("Singular matrix")
numpy.linalg.LinAlgError: Singular matrix

• overview:
  No output in md directory (empty)