Newbie question about feasibility

[david-priest]

Hi there,

I have a large CyTOF dataset (10s of millions of cells), with immune lineages sub-clustered in CATALYST by FlowSOM. Each immune lineage data and subclustering is stored in a separate single cell experiment (sce) object. I have another similar CyTOF dataset (~10 million cells) that I want to map onto the FlowSOM clustering of the first dataset. I was just wondering if this is at all possible using Seurat on a regular laptop?

Thanks very much.