diff --git a/.github/py-shiny/setup/action.yaml b/.github/py-shiny/setup/action.yaml
index dfa398f9f..0c50c616e 100644
--- a/.github/py-shiny/setup/action.yaml
+++ b/.github/py-shiny/setup/action.yaml
@@ -4,7 +4,7 @@ inputs:
   python-version:
     description: 'Python version to use'
     required: false
-    default: "3.12"
+    default: "3.13"
 runs:
   using: "composite"
   steps:
@@ -39,12 +39,6 @@ runs:
         run: |
           make ci-install-wheel
 
-      - name: Install backports.tarfile
-        if: ${{ startsWith(inputs.python-version, '3.8') }}
-        shell: bash
-        run: |
-          uv pip install backports.tarfile
-
       - name: Pip list
         shell: bash
         run: |
diff --git a/.github/workflows/build-docs.yaml b/.github/workflows/build-docs.yaml
index 818fe47e1..8d1d3c037 100644
--- a/.github/workflows/build-docs.yaml
+++ b/.github/workflows/build-docs.yaml
@@ -15,7 +15,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["3.12"]
+        python-version: ["3.13"]
       fail-fast: false
 
     steps:
diff --git a/.github/workflows/pytest.yaml b/.github/workflows/pytest.yaml
index ad355f70b..8f7621436 100644
--- a/.github/workflows/pytest.yaml
+++ b/.github/workflows/pytest.yaml
@@ -17,7 +17,7 @@ jobs:
     strategy:
       matrix:
         # "3.10" must be a string; otherwise it is interpreted as 3.1.
-        python-version: ["3.12", "3.11", "3.10", "3.9"]
+        python-version: ["3.13", "3.12", "3.11", "3.10", "3.9"]
         os: [ubuntu-latest, windows-latest, macOS-latest]
         exclude:
           - python-version: ${{ github.event.pull_request.draft && '3.11' }}
@@ -73,7 +73,7 @@ jobs:
         with:
           fetch-depth: 0
       - name: "Set up Python 3.10"
-        uses: actions/setup-python@v4
+        uses: actions/setup-python@v5
         with:
           python-version: "3.10"
       - name: Install dependencies
@@ -107,7 +107,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["3.12", "3.11", "3.10", "3.9"]
+        python-version: ["3.13", "3.12", "3.11", "3.10", "3.9"]
         browser: ["chromium", "firefox", "webkit"]
         exclude:
           - python-version: ${{ github.event.pull_request.draft && '3.11' }}
@@ -117,8 +117,6 @@ jobs:
           - browser: ${{ github.event.pull_request.draft && 'webkit' }}
           # There are many unexplained tests that fail on webkit w/ python 3.8, 3.9
           # Given the more recent versions of python work, we will exclude this combination
-          - browser: "webkit"
-            python-version: "3.8"
           - browser: "webkit"
             python-version: "3.9"
       fail-fast: false
@@ -157,7 +155,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["3.12", "3.11", "3.10", "3.9"]
+        python-version: ["3.13", "3.12", "3.11", "3.10", "3.9"]
         browser: ["chromium", "firefox", "webkit"]
         exclude:
           - python-version: ${{ github.event.pull_request.draft && '3.11' }}
diff --git a/pyproject.toml b/pyproject.toml
index c51a7d97f..0577e1ce6 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -26,6 +26,7 @@ classifiers = [
     "Programming Language :: Python :: 3.10",
     "Programming Language :: Python :: 3.11",
     "Programming Language :: Python :: 3.12",
+    "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
     "typing-extensions>=4.10.0",
@@ -54,8 +55,8 @@ theme = ["libsass>=0.23.0", "brand_yml>=0.1.0"]
 test = [
     "pytest>=6.2.4",
     "pytest-asyncio>=0.17.2",
-    "pytest-playwright>=0.3.0",
-    "playwright>=1.43.0",
+    "pytest-playwright>=0.5.2",
+    "playwright>=1.48.0",
     "pytest-xdist",
     "pytest-timeout",
     "pytest-rerunfailures",
@@ -86,7 +87,10 @@ test = [
     "faicons",
     "ridgeplot",
     "great_tables",
-    "modin[all]",
+    # modin depends on ray, which doesn't support Python 3.13
+    "modin[all];python_version<'3.13'",
+    # ray doesn't currently support Python 3.13
+    "ray;python_version<'3.13'",
     "polars",
     "dask[dataframe]",
     "pyarrow",
diff --git a/shiny/_datastructures.py b/shiny/_datastructures.py
index f2ac287ef..2a243d418 100644
--- a/shiny/_datastructures.py
+++ b/shiny/_datastructures.py
@@ -15,8 +15,6 @@ class PriorityQueueFIFO(Generic[T]):
     """
 
     def __init__(self) -> None:
-        # Using Tuple instead of tuple because in Python 3.8 and earlier, tuple isn't
-        # generic
         self._pq: PriorityQueue[tuple[int, int, T]] = PriorityQueue()
         self._counter: int = 0
 
diff --git a/shiny/_utils.py b/shiny/_utils.py
index fc0eaa21f..728fd94ec 100644
--- a/shiny/_utils.py
+++ b/shiny/_utils.py
@@ -72,7 +72,7 @@ def sort_keys_length(x: dict[str, T], descending: bool = False) -> dict[str, T]:
 
 
 def guess_mime_type(
-    url: "str | os.PathLike[str]",
+    url: str | os.PathLike[str],
     default: str = "application/octet-stream",
     strict: bool = True,
 ) -> str:
@@ -80,8 +80,6 @@ def guess_mime_type(
     Guess the MIME type of a file. This is a wrapper for mimetypes.guess_type, but it
     only returns the type (and not encoding), and it allows a default value.
     """
-    # Note that in the parameters above, "os.PathLike[str]" is in quotes to avoid
-    # "TypeError: 'ABCMeta' object is not subscriptable", in Python<=3.8.
     if url:
         # Work around issue #1601, some installations of Windows 10 return text/plain
         # as the mime type for .js files
diff --git a/shiny/render/_render.py b/shiny/render/_render.py
index 5cd608f6a..88c796bfc 100644
--- a/shiny/render/_render.py
+++ b/shiny/render/_render.py
@@ -4,9 +4,6 @@
 import os
 import sys
 import typing
-
-# `typing.Dict` sed for python 3.8 compatibility
-# Can use `dict` in python >= 3.9
 from typing import TYPE_CHECKING, Any, Callable, Literal, Optional, Union, cast
 
 from htmltools import Tag, TagAttrValue, TagChild
diff --git a/shiny/render/renderer/_renderer.py b/shiny/render/renderer/_renderer.py
index b79009c91..ce3cf3e26 100644
--- a/shiny/render/renderer/_renderer.py
+++ b/shiny/render/renderer/_renderer.py
@@ -336,9 +336,6 @@ def _auto_register(self) -> None:
                 self._auto_registered = True
 
 
-# Not inheriting from `WrapAsync[[], IT]` as python 3.8 needs typing extensions that
-# doesn't support `[]` for a ParamSpec definition. :-( Would be minimal/clean if we
-# could do `class AsyncValueFn(WrapAsync[[], IT]):`
 class AsyncValueFn(Generic[IT]):
     """
     App-supplied output value function which returns type `IT`.
diff --git a/tests/playwright/shiny/components/data_frame/data_type/app.py b/tests/playwright/shiny/components/data_frame/data_type/app.py
index 50c76b952..e18ede0b0 100644
--- a/tests/playwright/shiny/components/data_frame/data_type/app.py
+++ b/tests/playwright/shiny/components/data_frame/data_type/app.py
@@ -1,6 +1,13 @@
 from __future__ import annotations
 
-import modin.pandas as mpd  # pyright: ignore[reportMissingTypeStubs]
+import sys
+
+# Remove this conditional once modin is supported on Python 3.13
+if sys.version_info < (3, 13):
+    import modin.pandas as mpd  # pyright: ignore[reportMissingTypeStubs]
+else:
+    raise RuntimeError("This test is not supported on Python 3.13")
+
 import narwhals.stable.v1 as nw
 import palmerpenguins  # pyright: ignore[reportMissingTypeStubs]
 import polars as pl
diff --git a/tests/playwright/shiny/components/data_frame/data_type/test_df_data_type.py b/tests/playwright/shiny/components/data_frame/data_type/test_df_data_type.py
index d3c24e130..ff131eac9 100644
--- a/tests/playwright/shiny/components/data_frame/data_type/test_df_data_type.py
+++ b/tests/playwright/shiny/components/data_frame/data_type/test_df_data_type.py
@@ -1,5 +1,7 @@
 import re
+import sys
 
+import pytest
 from playwright.sync_api import Page
 
 from shiny.playwright import controller
@@ -39,6 +41,10 @@
 ]
 
 
+@pytest.mark.skipif(
+    sys.version_info[:2] == (3, 13),
+    reason="Skipping on Python 3.13, since modin is not supported on 3.13",
+)
 def test_data_frame_data_type(
     page: Page,
     local_app: ShinyAppProc,
diff --git a/tests/playwright/shiny/components/table/app.py b/tests/playwright/shiny/components/table/app.py
index 1a2a2a4e9..4b101bd4c 100644
--- a/tests/playwright/shiny/components/table/app.py
+++ b/tests/playwright/shiny/components/table/app.py
@@ -1,6 +1,13 @@
 from __future__ import annotations
 
-import modin.pandas as md  # pyright: ignore[reportMissingTypeStubs]
+import sys
+
+# Remove this conditional once modin is supported on Python 3.13
+if sys.version_info < (3, 13):
+    import modin.pandas as md  # pyright: ignore[reportMissingTypeStubs]
+else:
+    # This block executes for Python 3.13 and above
+    raise RuntimeError("This test is not supported on Python 3.13")
 import narwhals.stable.v1 as nw
 import palmerpenguins  # pyright: ignore[reportMissingTypeStubs]
 
diff --git a/tests/playwright/shiny/components/table/test_table.py b/tests/playwright/shiny/components/table/test_table.py
index d04bcd39d..0f5f27f15 100644
--- a/tests/playwright/shiny/components/table/test_table.py
+++ b/tests/playwright/shiny/components/table/test_table.py
@@ -1,11 +1,17 @@
 import re
+import sys
 
+import pytest
 from playwright.sync_api import Page
 
 from shiny.playwright import controller
 from shiny.run import ShinyAppProc
 
 
+@pytest.mark.skipif(
+    sys.version_info >= (3, 13),
+    reason="Skipping on Python 3.13 and above, since modin is not supported on these versions",
+)
 def test_table_data_support(page: Page, local_app: ShinyAppProc) -> None:
     page.goto(local_app.url)