Skip to content

Address issues with heuristic placement #29

@pierrebarbera

Description

@pierrebarbera

For "weird" sequences that don't fit in the tree, or may not align correctly, or are just plain wrong, we have observed a tendency of them being placed on longer branches of a reference tree, sometimes with a high to very high LWR. While some of these may be caught by filtering based on pendant length of the queries, the real problem lies with with the heuristic preplacement phase which is the likely culprit. Specifically, during this phase queries are inserted using a default pendant length of 0.9, which for some cases may simply be too long.

This also touches on identification of "novel" lineages in the query data, which is usually a goal of placement analyses. However the primary goal is to re-establish LWR as the primary criterion for placement confidence.

Metadata

Metadata

Assignees

No one assigned

    Labels

    No labels
    No labels

    Projects

    No projects

    Milestone

    No milestone

    Relationships

    None yet

    Development

    No branches or pull requests

    Issue actions