diff --git a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParser.java b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParser.java
index ef0c5e08a719..305bfe3a771b 100644
--- a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParser.java
+++ b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParser.java
@@ -892,6 +892,24 @@ DbInfo.Builder doParse(String jdbcUrl, DbInfo.Builder builder) {
 
       return builder;
     }
+  },
+  /**
+   * <a
+   * href="https://clickhouse.com/docs/integrations/language-clients/java/jdbc#configuration">Driver
+   * configuration doc</a> mentions that besides <code>clickhouse</code> <code>ch</code> could also
+   * be used but ClickHouse Connection implementation always returns full prefix <code>
+   * jdbc:clickhouse:</code>
+   */
+  CLICKHOUSE("clickhouse") {
+    @Override
+    DbInfo.Builder doParse(String jdbcUrl, DbInfo.Builder builder) {
+      String clickhouseUrl = jdbcUrl.substring("clickhouse:".length());
+      int typeEndIndex = clickhouseUrl.indexOf("://");
+      if (typeEndIndex > 0) {
+        builder.subtype(clickhouseUrl.substring(0, typeEndIndex));
+      }
+      return GENERIC_URL_LIKE.doParse(clickhouseUrl, builder);
+    }
   };
 
   private static final Logger logger = Logger.getLogger(JdbcConnectionUrlParser.class.getName());
@@ -1079,6 +1097,8 @@ private static String toDbSystem(String type) {
         return DbSystemValues.MSSQL;
       case "sap": // SAP Hana
         return DbSystemValues.HANADB;
+      case "clickhouse": // ClickHouse
+        return DbSystemValues.CLICKHOUSE;
       default:
         return DbSystemValues.OTHER_SQL; // Unknown DBMS
     }
@@ -1098,6 +1118,7 @@ private static final class DbSystemValues {
     static final String DERBY = "derby";
     static final String MARIADB = "mariadb";
     static final String H2 = "h2";
+    static final String CLICKHOUSE = "clickhouse";
 
     private DbSystemValues() {}
   }
diff --git a/instrumentation/jdbc/library/src/test/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParserTest.java b/instrumentation/jdbc/library/src/test/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParserTest.java
index bc90cbc72908..4abcd63047b4 100644
--- a/instrumentation/jdbc/library/src/test/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParserTest.java
+++ b/instrumentation/jdbc/library/src/test/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcConnectionUrlParserTest.java
@@ -207,6 +207,35 @@ public Stream<? extends Arguments> provideArguments(ExtensionContext context) {
     }
   }
 
+  @ParameterizedTest(name = "{index}: {0}")
+  @ArgumentsSource(ClickHouseProvider.class)
+  void testClickHouseParsing(ParseTestArgument argument) {
+    testVerifySystemSubtypeParsingOfUrl(argument);
+  }
+
+  static final class ClickHouseProvider implements ArgumentsProvider {
+    @Override
+    public Stream<? extends Arguments> provideArguments(ExtensionContext context) {
+      return args(
+          // https://clickhouse.com/docs/integrations/language-clients/java/jdbc#configuration
+          arg("jdbc:clickhouse:http://localhost:8123/mydb")
+              .setShortUrl("clickhouse:http://localhost:8123")
+              .setSystem("clickhouse")
+              .setSubtype("http")
+              .setHost("localhost")
+              .setPort(8123)
+              .setDb("mydb")
+              .build(),
+          arg("jdbc:clickhouse:https://localhost:8443?ssl=true")
+              .setShortUrl("clickhouse:https://localhost:8443")
+              .setSystem("clickhouse")
+              .setSubtype("https")
+              .setHost("localhost")
+              .setPort(8443)
+              .build());
+    }
+  }
+
   @ParameterizedTest(name = "{index}: {0}")
   @ArgumentsSource(PostgresProvider.class)
   void testPostgresParsing(ParseTestArgument argument) {