diff --git a/README.rst b/README.rst
index a0d28e6..3865a62 100644
--- a/README.rst
+++ b/README.rst
@@ -10,7 +10,7 @@ The bindings generator generates ctypes-bindings from the include
 files defining the public API. The same generated module should be
 compatible with various versions of libvlc 2.* and 3.*. However, there
 may be incompatible changes between major versions. Versioned bindings
-for 2.2 and 3.0 are provided in the repository.
+for 2.2 and 3.0 are provided in the repository. Note: When using 64-bit Python, make sure to use 64-bit VLC, and when using 32-bit Python, make sure to use 32-bit VLC. 
 
 License
 -------