Skip to content

[BulkRNASeq] Handle processing with experimental groups where N = 1 #38

@J-81

Description

@J-81

Description

Certain datasets have experimental groups of single samples.
This current breaks differential expression approaches and likely means differential expression will be impossible.

Steps to Reproduce

  1. Create subset of Runsheet rows with at least one group with N = 1 samples

Expected Behavior

Processing workflows should identify these cases and process up to DE but not run DE.
In these cases, normalized data should be available for release.

Actual Behavior

Processing attempts DE and raises exception.

Impact on Data

Non silent bug: no processed data released with this causing an issue.
Known to impact 1 dataset at start of this issue.

Additional Context

Provide any additional information or context that might be relevant to the issue.

Possible Solution (optional)

Process through normalization, then stop.
This will require some modification for post processing which assumes complete processing.

Metadata

Metadata

Assignees

No one assigned

    Labels

    No labels
    No labels

    Type

    No type

    Projects

    No projects

    Milestone

    No milestone

    Relationships

    None yet

    Development

    No branches or pull requests

    Issue actions