diff --git a/src/mcp/server/fastmcp/tools/base.py b/src/mcp/server/fastmcp/tools/base.py
index 3d8827ed7..e9d5b296e 100644
--- a/src/mcp/server/fastmcp/tools/base.py
+++ b/src/mcp/server/fastmcp/tools/base.py
@@ -1,6 +1,7 @@
 from __future__ import annotations as _annotations
 
 import functools
+import httpx
 import inspect
 from collections.abc import Callable
 from functools import cached_property
@@ -106,6 +107,12 @@ async def run(
                 result = self.fn_metadata.convert_result(result)
 
             return result
+        except httpx.HTTPStatusError as e:
+            try:
+                error_detail = e.response.json()
+            except:
+                error_detail = e.response.text
+            raise ToolError(f"Error executing tool {self.name}: [{e.response.status_code}] {error_detail}")
         except Exception as e:
             raise ToolError(f"Error executing tool {self.name}: {e}") from e
 
diff --git a/tests/server/fastmcp/test_tool_manager.py b/tests/server/fastmcp/test_tool_manager.py
index 27e16cc8e..137ff8b4e 100644
--- a/tests/server/fastmcp/test_tool_manager.py
+++ b/tests/server/fastmcp/test_tool_manager.py
@@ -313,6 +313,55 @@ def name_shrimp(tank: MyShrimpTank, ctx: Context) -> list[str]:
         )
         assert result == ["rex", "gertrude"]
 
+    @pytest.mark.anyio
+    async def test_tool_run_httpx_json_error(self):
+        """Test Tool.run() handling HTTPStatusError with JSON response."""
+        import httpx
+        from unittest.mock import Mock
+
+        def tool_with_httpx_error(x: int) -> str:
+            mock_response = Mock()
+            mock_response.status_code = 404
+            mock_response.json.return_value = {"error": "Not found", "code": "RESOURCE_NOT_FOUND"}
+            raise httpx.HTTPStatusError("Not found", request=Mock(), response=mock_response)
+
+        manager = ToolManager()
+        tool = manager.add_tool(tool_with_httpx_error)
+
+        with pytest.raises(ToolError, match="Error executing tool tool_with_httpx_error: [404]"):
+            await tool.run({"x": 42})
+
+    @pytest.mark.anyio
+    async def test_tool_run_httpx_text_error(self):
+        """Test Tool.run() handling HTTPStatusError with text response."""
+        import httpx
+        from unittest.mock import Mock
+
+        def tool_with_httpx_text_error(x: int) -> str:
+            mock_response = Mock()
+            mock_response.status_code = 500
+            mock_response.json.side_effect = Exception("Not JSON")
+            mock_response.text = "Internal Server Error"
+            raise httpx.HTTPStatusError("Server error", request=Mock(), response=mock_response)
+
+        manager = ToolManager()
+        tool = manager.add_tool(tool_with_httpx_text_error)
+
+        with pytest.raises(ToolError, match="Error executing tool tool_with_httpx_text_error: [500] Internal Server Error"):
+            await tool.run({"x": 42})
+
+    @pytest.mark.anyio
+    async def test_tool_run_generic_exception(self):
+        """Test Tool.run() handling generic exceptions."""
+        def tool_with_error(x: int) -> str:
+            raise ValueError("Something went wrong")
+
+        manager = ToolManager()
+        tool = manager.add_tool(tool_with_error)
+
+        with pytest.raises(ToolError, match="Error executing tool tool_with_error: Something went wrong"):
+            await tool.run({"x": 42})
+
 
 class TestToolSchema:
     @pytest.mark.anyio