MySQL "Prepared Statement needs to be re-prepared"

[camblomquist]

I ported an existing database interface to sqlx. The previous interface did not use prepared statements at all while this version uses them heavily.
Now every so often, a query will fail with the error message "Prepared statement needs to be re-prepared." This error is hard to track, it occurs sporadically and will go away on its own just to come back later. Eventually, I believe we will be working on a different instance such that any issues resulting from strange interactions between old and new databases should go away. In the meantime, I'm wondering if there is anything I should be doing when using sqlx to avoid this error.