The problem of gene family variation

[keeppeace111]

hi，I met some problems:
When I run CAFE5, even if the gene family variance is reduced to 4, it still prompts me that the variance is too large

Families with largest size differentials:
OG0001701: 4
OG0008722: 4
OG0001666: 4
OG0001671: 4
OG0001679: 4
OG0001680: 4
OG0001682: 4
OG0003550: 4
OG0001689: 4
OG0001694: 4
OG0001658: 4
OG0001711: 4
OG0001718: 4
OG0001721: 4
OG0001724: 4
OG0001727: 4
OG0001746: 4
OG0001752: 4
OG0003504: 4
OG0001755: 4

You may want to try removing the top few families with the largest difference
between the max and min counts and then re-run the analysis.

Failed to initialize any reasonable values

[benfulton]

There are other reasons why CAFE might not be able to find values. Your tree may be too deep, for example.