choose the best estimator for each cell type

[zhouyuan479]

Hi,

Thanks for the very useful CETYGO package!
A tutorial on the human brain reference panels showed how to extract the best estimator for each cell type as follows.

predPropBest<-cbind(predPropAll[["ANOVA"]][[1]][,c("NeuNNeg_SOX10Neg", "NeuNPos")], predPropAll[["IDOL"]][[5]][,c("NeuNNeg_Sox10Neg_IRF8Pos","NeuNNeg_Sox10Neg_IRF8Neg")], predPropAll[["ANOVA"]][[3]][,c("SATB2Neg", "SATB2Pos")], predPropAll[["ANOVA"]][[6]][,c("NeuNNeg", "NeuNPos_SOX6Pos", "NeuNPos_SOX6Neg")], predPropAll[["IDOL"]][[4]][,"NeuNNeg_SOX10Pos"])
colnames(predPropBest)[10]<-"NeuNNeg_SOX10Pos"

I am confused how can I know the best estimator for each cell type?

Thanks!
Yuan

[ejh243]

Hi Yuan,

Apologies for the slow response. The best estimator for each cell type is selected based on the results in this manuscript: https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01827-y.

Hope that helps.

Eilis