diff --git a/src/BuiltInTools/dotnet-watch/Browser/BrowserConnector.cs b/src/BuiltInTools/dotnet-watch/Browser/BrowserConnector.cs
index 9d3c61515bf8..2cd69c10f85b 100644
--- a/src/BuiltInTools/dotnet-watch/Browser/BrowserConnector.cs
+++ b/src/BuiltInTools/dotnet-watch/Browser/BrowserConnector.cs
@@ -299,11 +299,8 @@ public bool IsServerSupported(ProjectGraphNode projectNode, HotReloadAppModel ap
 
         private LaunchSettingsProfile GetLaunchProfile(ProjectOptions projectOptions)
         {
-            var projectDirectory = Path.GetDirectoryName(projectOptions.ProjectPath);
-            Debug.Assert(projectDirectory != null);
-
             return (projectOptions.NoLaunchProfile == true
-                ? null : LaunchSettingsProfile.ReadLaunchProfile(projectDirectory, projectOptions.LaunchProfileName, context.Reporter)) ?? new();
+                ? null : LaunchSettingsProfile.ReadLaunchProfile(projectOptions.ProjectPath, projectOptions.LaunchProfileName, context.Reporter)) ?? new();
         }
     }
 }
diff --git a/src/BuiltInTools/dotnet-watch/Process/LaunchSettingsProfile.cs b/src/BuiltInTools/dotnet-watch/Process/LaunchSettingsProfile.cs
index 75994a9bff86..6aec6dee3a6b 100644
--- a/src/BuiltInTools/dotnet-watch/Process/LaunchSettingsProfile.cs
+++ b/src/BuiltInTools/dotnet-watch/Process/LaunchSettingsProfile.cs
@@ -2,8 +2,11 @@
 // The .NET Foundation licenses this file to you under the MIT license.
 
 
+using System.Diagnostics;
 using System.Text.Json;
 using System.Text.Json.Serialization;
+using Microsoft.DotNet.Cli.Commands;
+using Microsoft.DotNet.Cli.Commands.Run;
 
 namespace Microsoft.DotNet.Watch
 {
@@ -22,10 +25,30 @@ internal sealed class LaunchSettingsProfile
         public bool LaunchBrowser { get; init; }
         public string? LaunchUrl { get; init; }
 
-        internal static LaunchSettingsProfile? ReadLaunchProfile(string projectDirectory, string? launchProfileName, IReporter reporter)
+        internal static LaunchSettingsProfile? ReadLaunchProfile(string projectPath, string? launchProfileName, IReporter reporter)
         {
-            var launchSettingsPath = Path.Combine(projectDirectory, "Properties", "launchSettings.json");
-            if (!File.Exists(launchSettingsPath))
+            var projectDirectory = Path.GetDirectoryName(projectPath);
+            Debug.Assert(projectDirectory != null);
+
+            var launchSettingsPath = CommonRunHelpers.GetPropertiesLaunchSettingsPath(projectDirectory, "Properties");
+            bool hasLaunchSettings = File.Exists(launchSettingsPath);
+
+            var projectNameWithoutExtension = Path.GetFileNameWithoutExtension(projectPath);
+            var runJsonPath = CommonRunHelpers.GetFlatLaunchSettingsPath(projectDirectory, projectNameWithoutExtension);
+            bool hasRunJson = File.Exists(runJsonPath);
+
+            if (hasLaunchSettings)
+            {
+                if (hasRunJson)
+                {
+                    reporter.Warn(string.Format(CliCommandStrings.RunCommandWarningRunJsonNotUsed, runJsonPath, launchSettingsPath));
+                }
+            }
+            else if (hasRunJson)
+            {
+                launchSettingsPath = runJsonPath;
+            }
+            else
             {
                 return null;
             }
@@ -39,7 +62,7 @@ internal sealed class LaunchSettingsProfile
             }
             catch (Exception ex)
             {
-                reporter.Verbose($"Error reading launchSettings.json: {ex}.");
+                reporter.Verbose($"Error reading '{launchSettingsPath}': {ex}.");
                 return null;
             }
 
diff --git a/src/Cli/dotnet/Commands/CliCommandStrings.resx b/src/Cli/dotnet/Commands/CliCommandStrings.resx
index 32fd74595df4..633b991c9644 100644
--- a/src/Cli/dotnet/Commands/CliCommandStrings.resx
+++ b/src/Cli/dotnet/Commands/CliCommandStrings.resx
@@ -692,7 +692,8 @@ dotnet.config is a name don't translate.</comment>
     <value>Do not use arguments specified in launch profile to run the application.</value>
   </data>
   <data name="CommandOptionNoLaunchProfileDescription" xml:space="preserve">
-    <value>Do not attempt to use launchSettings.json to configure the application.</value>
+    <value>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</value>
+    <comment>{Locked="launchSettings.json"}{Locked=".run.json"}</comment>
   </data>
   <data name="CommandOptionProjectDescription" xml:space="preserve">
     <value>The path to the project file to run (defaults to the current directory if there is only one project).</value>
@@ -766,8 +767,8 @@ dotnet.config is a name don't translate.</comment>
     <value>Description</value>
   </data>
   <data name="DeserializationExceptionMessage" xml:space="preserve">
-    <value>An error was encountered when reading launchSettings.json.
-{0}</value>
+    <value>An error was encountered when reading '{0}': {1}</value>
+    <comment>{0} is file path. {1} is exception message.</comment>
   </data>
   <data name="DetailDescription" xml:space="preserve">
     <value>Show detail result of the query.</value>
@@ -1743,7 +1744,12 @@ The default is to publish a framework-dependent application.</value>
 {1}</value>
   </data>
   <data name="RunCommandExceptionCouldNotLocateALaunchSettingsFile" xml:space="preserve">
-    <value>The specified launch profile '{0}' could not be located.</value>
+    <value>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</value>
+  </data>
+  <data name="RunCommandWarningRunJsonNotUsed" xml:space="preserve">
+    <value>Warning: Settings from '{0}' are not used because '{1}' has precedence.</value>
+    <comment>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</comment>
   </data>
   <data name="RunCommandExceptionMultipleProjects" xml:space="preserve">
     <value>Specify which project file to use because {0} contains more than one project file.</value>
diff --git a/src/Cli/dotnet/Commands/Run/CommonRunHelpers.cs b/src/Cli/dotnet/Commands/Run/CommonRunHelpers.cs
index 42319ae30e39..c9b0880a383d 100644
--- a/src/Cli/dotnet/Commands/Run/CommonRunHelpers.cs
+++ b/src/Cli/dotnet/Commands/Run/CommonRunHelpers.cs
@@ -36,4 +36,10 @@ public static Dictionary<string, string> GetGlobalPropertiesFromArgs(string[] ar
         }
         return globalProperties;
     }
+
+    public static string GetPropertiesLaunchSettingsPath(string directoryPath, string propertiesDirectoryName)
+        => Path.Combine(directoryPath, propertiesDirectoryName, "launchSettings.json");
+
+    public static string GetFlatLaunchSettingsPath(string directoryPath, string projectNameWithoutExtension)
+        => Path.Join(directoryPath, $"{projectNameWithoutExtension}.run.json");
 }
diff --git a/src/Cli/dotnet/Commands/Run/LaunchSettings/LaunchSettingsManager.cs b/src/Cli/dotnet/Commands/Run/LaunchSettings/LaunchSettingsManager.cs
index c46fee8aaa15..a1776027476d 100644
--- a/src/Cli/dotnet/Commands/Run/LaunchSettings/LaunchSettingsManager.cs
+++ b/src/Cli/dotnet/Commands/Run/LaunchSettings/LaunchSettingsManager.cs
@@ -22,8 +22,9 @@ static LaunchSettingsManager()
         };
     }
 
-    public static LaunchSettingsApplyResult TryApplyLaunchSettings(string launchSettingsJsonContents, string? profileName = null)
+    public static LaunchSettingsApplyResult TryApplyLaunchSettings(string launchSettingsPath, string? profileName = null)
     {
+        var launchSettingsJsonContents = File.ReadAllText(launchSettingsPath);
         try
         {
             var jsonDocumentOptions = new JsonDocumentOptions
@@ -115,7 +116,7 @@ public static LaunchSettingsApplyResult TryApplyLaunchSettings(string launchSett
         }
         catch (JsonException ex)
         {
-            return new LaunchSettingsApplyResult(false, string.Format(CliCommandStrings.DeserializationExceptionMessage, ex.Message));
+            return new LaunchSettingsApplyResult(false, string.Format(CliCommandStrings.DeserializationExceptionMessage, launchSettingsPath, ex.Message));
         }
     }
 
diff --git a/src/Cli/dotnet/Commands/Run/RunCommand.cs b/src/Cli/dotnet/Commands/Run/RunCommand.cs
index f29151de4e6d..e33180e95cb6 100644
--- a/src/Cli/dotnet/Commands/Run/RunCommand.cs
+++ b/src/Cli/dotnet/Commands/Run/RunCommand.cs
@@ -202,13 +202,9 @@ internal bool TryGetLaunchProfileSettingsIfNeeded(out ProjectLaunchSettingsModel
             return true;
         }
 
-        var launchSettingsPath = ReadCodeFromStdin ? null : TryFindLaunchSettings(ProjectFileFullPath ?? EntryPointFileFullPath!);
-        if (!File.Exists(launchSettingsPath))
+        var launchSettingsPath = ReadCodeFromStdin ? null : TryFindLaunchSettings(projectOrEntryPointFilePath: ProjectFileFullPath ?? EntryPointFileFullPath!, launchProfile: LaunchProfile);
+        if (launchSettingsPath is null)
         {
-            if (!string.IsNullOrEmpty(LaunchProfile))
-            {
-                Reporter.Error.WriteLine(string.Format(CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile, launchSettingsPath).Bold().Red());
-            }
             return true;
         }
 
@@ -221,8 +217,7 @@ internal bool TryGetLaunchProfileSettingsIfNeeded(out ProjectLaunchSettingsModel
 
         try
         {
-            var launchSettingsFileContents = File.ReadAllText(launchSettingsPath);
-            var applyResult = LaunchSettingsManager.TryApplyLaunchSettings(launchSettingsFileContents, LaunchProfile);
+            var applyResult = LaunchSettingsManager.TryApplyLaunchSettings(launchSettingsPath, LaunchProfile);
             if (!applyResult.Success)
             {
                 Reporter.Error.WriteLine(string.Format(CliCommandStrings.RunCommandExceptionCouldNotApplyLaunchSettings, profileName, applyResult.FailureReason).Bold().Red());
@@ -241,13 +236,9 @@ internal bool TryGetLaunchProfileSettingsIfNeeded(out ProjectLaunchSettingsModel
 
         return true;
 
-        static string? TryFindLaunchSettings(string projectOrEntryPointFilePath)
+        static string? TryFindLaunchSettings(string projectOrEntryPointFilePath, string? launchProfile)
         {
-            var buildPathContainer = File.Exists(projectOrEntryPointFilePath) ? Path.GetDirectoryName(projectOrEntryPointFilePath) : projectOrEntryPointFilePath;
-            if (buildPathContainer is null)
-            {
-                return null;
-            }
+            var buildPathContainer = Path.GetDirectoryName(projectOrEntryPointFilePath)!;
 
             string propsDirectory;
 
@@ -263,8 +254,37 @@ internal bool TryGetLaunchProfileSettingsIfNeeded(out ProjectLaunchSettingsModel
                 propsDirectory = "Properties";
             }
 
-            var launchSettingsPath = Path.Combine(buildPathContainer, propsDirectory, "launchSettings.json");
-            return launchSettingsPath;
+            string launchSettingsPath = CommonRunHelpers.GetPropertiesLaunchSettingsPath(buildPathContainer, propsDirectory);
+            bool hasLaunchSetttings = File.Exists(launchSettingsPath);
+
+            string appName = Path.GetFileNameWithoutExtension(projectOrEntryPointFilePath);
+            string runJsonPath = CommonRunHelpers.GetFlatLaunchSettingsPath(buildPathContainer, appName);
+            bool hasRunJson = File.Exists(runJsonPath);
+
+            if (hasLaunchSetttings)
+            {
+                if (hasRunJson)
+                {
+                    Reporter.Output.WriteLine(string.Format(CliCommandStrings.RunCommandWarningRunJsonNotUsed, runJsonPath, launchSettingsPath).Yellow());
+                }
+
+                return launchSettingsPath;
+            }
+
+            if (hasRunJson)
+            {
+                return runJsonPath;
+            }
+
+            if (!string.IsNullOrEmpty(launchProfile))
+            {
+                Reporter.Error.WriteLine(string.Format(CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile, launchProfile, $"""
+                    {launchSettingsPath}
+                    {runJsonPath}
+                    """).Bold().Red());
+            }
+
+            return null;
         }
     }
 
@@ -573,6 +593,7 @@ public static RunCommand FromParseResult(ParseResult parseResult)
             out string? entryPointFilePath);
 
         bool noBuild = parseResult.HasOption(RunCommandParser.NoBuildOption);
+        string launchProfile = parseResult.GetValue(RunCommandParser.LaunchProfileOption) ?? string.Empty;
 
         if (readCodeFromStdin && entryPointFilePath != null)
         {
@@ -583,6 +604,11 @@ public static RunCommand FromParseResult(ParseResult parseResult)
                 throw new GracefulException(CliCommandStrings.InvalidOptionForStdin, RunCommandParser.NoBuildOption.Name);
             }
 
+            if (!string.IsNullOrWhiteSpace(launchProfile))
+            {
+                throw new GracefulException(CliCommandStrings.InvalidOptionForStdin, RunCommandParser.LaunchProfileOption.Name);
+            }
+
             // If '-' is specified as the input file, read all text from stdin into a temporary file and use that as the entry point.
             // We create a new directory for each file so other files are not included in the compilation.
             // We fail if the file already exists to avoid reusing the same file for multiple stdin runs (in case the random name is duplicate).
@@ -605,7 +631,7 @@ public static RunCommand FromParseResult(ParseResult parseResult)
             noBuild: noBuild,
             projectFileFullPath: projectFilePath,
             entryPointFileFullPath: entryPointFilePath,
-            launchProfile: parseResult.GetValue(RunCommandParser.LaunchProfileOption) ?? string.Empty,
+            launchProfile: launchProfile,
             noLaunchProfile: parseResult.HasOption(RunCommandParser.NoLaunchProfileOption),
             noLaunchProfileArguments: parseResult.HasOption(RunCommandParser.NoLaunchProfileArgumentsOption),
             noRestore: parseResult.HasOption(RunCommandParser.NoRestoreOption) || parseResult.HasOption(RunCommandParser.NoBuildOption),
diff --git a/src/Cli/dotnet/Commands/Test/SolutionAndProjectUtility.cs b/src/Cli/dotnet/Commands/Test/SolutionAndProjectUtility.cs
index 53fe677a4a44..bbad54fd096d 100644
--- a/src/Cli/dotnet/Commands/Test/SolutionAndProjectUtility.cs
+++ b/src/Cli/dotnet/Commands/Test/SolutionAndProjectUtility.cs
@@ -248,7 +248,7 @@ public static IEnumerable<ParallelizableTestModuleGroupWithSequentialInnerModule
         string projectFullPath = project.GetPropertyValue(ProjectProperties.ProjectFullPath);
 
         // TODO: Support --launch-profile and pass it here.
-        var launchSettings = TryGetLaunchProfileSettings(Path.GetDirectoryName(projectFullPath)!, project.GetPropertyValue(ProjectProperties.AppDesignerFolder), noLaunchProfile, profileName: null);
+        var launchSettings = TryGetLaunchProfileSettings(Path.GetDirectoryName(projectFullPath)!, Path.GetFileNameWithoutExtension(projectFullPath), project.GetPropertyValue(ProjectProperties.AppDesignerFolder), noLaunchProfile, profileName: null);
 
         return new TestModule(runProperties, PathUtility.FixFilePath(projectFullPath), targetFramework, isTestingPlatformApplication, isTestProject, launchSettings, project.GetPropertyValue(ProjectProperties.TargetPath));
 
@@ -270,20 +270,36 @@ static RunProperties GetRunProperties(ProjectInstance project, ICollection<ILogg
         }
     }
 
-    private static ProjectLaunchSettingsModel? TryGetLaunchProfileSettings(string projectDirectory, string appDesignerFolder, bool noLaunchProfile, string? profileName)
+    private static ProjectLaunchSettingsModel? TryGetLaunchProfileSettings(string projectDirectory, string projectNameWithoutExtension, string appDesignerFolder, bool noLaunchProfile, string? profileName)
     {
         if (noLaunchProfile)
         {
             return null;
         }
 
-        var launchSettingsPath = Path.Combine(projectDirectory, appDesignerFolder, "launchSettings.json");
-        if (!File.Exists(launchSettingsPath))
+        var launchSettingsPath = CommonRunHelpers.GetPropertiesLaunchSettingsPath(projectDirectory, appDesignerFolder);
+        bool hasLaunchSettings = File.Exists(launchSettingsPath);
+
+        var runJsonPath = CommonRunHelpers.GetFlatLaunchSettingsPath(projectDirectory, projectNameWithoutExtension);
+        bool hasRunJson = File.Exists(runJsonPath);
+
+        if (hasLaunchSettings)
+        {
+            if (hasRunJson)
+            {
+                Reporter.Output.WriteLine(string.Format(CliCommandStrings.RunCommandWarningRunJsonNotUsed, runJsonPath, launchSettingsPath).Yellow());
+            }
+        }
+        else if (hasRunJson)
+        {
+            launchSettingsPath = runJsonPath;
+        }
+        else
         {
             return null;
         }
 
-        var result = LaunchSettingsManager.TryApplyLaunchSettings(File.ReadAllText(launchSettingsPath), profileName);
+        var result = LaunchSettingsManager.TryApplyLaunchSettings(launchSettingsPath, profileName);
         if (!result.Success)
         {
             Reporter.Error.WriteLine(string.Format(CliCommandStrings.RunCommandExceptionCouldNotApplyLaunchSettings, profileName, result.FailureReason).Bold().Red());
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.cs.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.cs.xlf
index 0e2973e2a078..b0e204dab350 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.cs.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.cs.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Ke konfiguraci aplikace nepoužívejte launchSettings.json.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Ke konfiguraci aplikace nepoužívejte launchSettings.json.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Při načítání launchSettings.json došlo k chybě.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ Ve výchozím nastavení je publikována aplikace závislá na architektuře.</t
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Zadaný profil spuštění {0} se nenašel.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Cílem projektu je více architektur. Pomocí parametru {0} určete, která arch
         <target state="translated">{0} není platný soubor projektu.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Konfigurace pro spuštění. Výchozí možností pro většinu projektů je Debug.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.de.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.de.xlf
index e41822e1a239..d76526f597fa 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.de.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.de.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Versuchen Sie nicht, "launchSettings.json" zum Konfigurieren der Anwendung zu verwenden.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Versuchen Sie nicht, "launchSettings.json" zum Konfigurieren der Anwendung zu verwenden.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Beim Lesen von "launchSettings.json" ist ein Fehler aufgetreten.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ Standardmäßig wird eine Framework-abhängige Anwendung veröffentlicht.</targe
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Das angegebene Startprofil "{0}" wurde nicht gefunden.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Ihr Projekt verwendet mehrere Zielframeworks. Geben Sie über "{0}" an, welches
         <target state="translated">"{0}" ist keine gültige Projektdatei.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Die Konfiguration für die Ausführung. Der Standardwert für die meisten Projekte ist "Debug".</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.es.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.es.xlf
index f6697ec7dde0..7c4de260eebb 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.es.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.es.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">No intente usar launchSettings.json para configurar la aplicación.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">No intente usar launchSettings.json para configurar la aplicación.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Se produjo un error al leer launchSettings.json.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ El valor predeterminado es publicar una aplicación dependiente del marco.</targ
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">No se ha podido encontrar el perfil de inicio especificado "{0}".</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Su proyecto tiene como destino varias plataformas. Especifique la que quiere usa
         <target state="translated">"{0}" no es un archivo de proyecto válido.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">La configuración para la que se ejecuta. El valor predeterminado para la mayoría de los proyectos es "Debug".</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.fr.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.fr.xlf
index 76d2ea3aa52c..3ee4990dc684 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.fr.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.fr.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">N'essayez pas d'utiliser launchSettings.json pour configurer l'application.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">N'essayez pas d'utiliser launchSettings.json pour configurer l'application.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Une erreur s'est produite durant la lecture de launchSettings.json.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ La valeur par défaut est de publier une application dépendante du framework.</
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Le profil de lancement spécifié '{0}' n'a pas pu être localisé.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Votre projet cible plusieurs frameworks. Spécifiez le framework à exécuter à
         <target state="translated">'{0}' n'est pas un fichier projet valide.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Configuration pour laquelle l'exécution est effectuée. La valeur par défaut pour la plupart des projets est 'Debug'.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.it.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.it.xlf
index 38b6b017b813..7f629a1c87b3 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.it.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.it.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Non prova a usare launchSettings.json per configurare l'applicazione.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Non prova a usare launchSettings.json per configurare l'applicazione.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">È stato rilevato un errore durante la lettura di launchSettings.json.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ Per impostazione predefinita, viene generato un pacchetto dipendente dal framewo
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Il profilo di avvio specificato '{0}' non è stato trovato.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Il progetto è destinato a più framework. Specificare il framework da eseguire
         <target state="translated">'{0}' non è un file di progetto valido.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Configurazione da usare per l'esecuzione. L'impostazione predefinita per la maggior parte dei progetti è 'Debug'.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ja.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ja.xlf
index 49028a409f26..eb4df72524c0 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ja.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ja.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">launchSettings.json の使用によるアプリケーションの構成は行わないでください。</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">launchSettings.json の使用によるアプリケーションの構成は行わないでください。</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">launchSettings.json を読み取るときにエラーが発生しました。
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ The default is to publish a framework-dependent application.</source>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">指定された起動プロファイル '{0}' が見つかりませんでした。</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Your project targets multiple frameworks. Specify which framework to run using '
         <target state="translated">'{0}' は有効なプロジェクト ファイルではありません。</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">実行する対象の構成。大部分のプロジェクトで、既定値は 'Debug' です。</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ko.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ko.xlf
index b420a2b67b48..465c1b74813e 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ko.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ko.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">launchSettings.json을 사용하여 애플리케이션을 구성하지 마세요.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">launchSettings.json을 사용하여 애플리케이션을 구성하지 마세요.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">launchSettings.json을 읽는 동안 오류가 발생했습니다.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ The default is to publish a framework-dependent application.</source>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">지정한 '{0}' 시작 프로필을 찾을 수 없습니다.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Your project targets multiple frameworks. Specify which framework to run using '
         <target state="translated">'{0}'은(는) 유효한 프로젝트 파일이 아닙니다.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">실행할 구성입니다. 대부분의 프로젝트에서 기본값은 'Debug'입니다.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pl.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pl.xlf
index ea78cbf5c69f..8106cd6cb59a 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pl.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pl.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Nie próbuj konfigurować aplikacji za pomocą pliku launchSettings.json.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Nie próbuj konfigurować aplikacji za pomocą pliku launchSettings.json.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Wystąpił błąd podczas odczytywania pliku launchSettings.json.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ Domyślnie publikowana jest aplikacja zależna od struktury.</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Nie można odnaleźć określonego profilu uruchamiania „{0}”.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Projekt ma wiele platform docelowych. Określ platformę do uruchomienia przy u
         <target state="translated">„{0}” nie jest prawidłowym plikiem projektu.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Konfiguracja, którą należy uruchomić. W przypadku większości projektów ustawienie domyślne to „Debugowanie”.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pt-BR.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pt-BR.xlf
index 8839bcd13e80..fddba152d962 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pt-BR.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.pt-BR.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Não tente usar o launchSettings.json para configurar o aplicativo.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Não tente usar o launchSettings.json para configurar o aplicativo.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">Um erro foi encontrado durante a leitura do launchSettings.json.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ O padrão é publicar uma aplicação dependente de framework.</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">O perfil de inicialização especificado '{0}' não pôde ser localizado.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Ele tem diversas estruturas como destino. Especifique que estrutura executar usa
         <target state="translated">'{0}' não é um arquivo de projeto válido.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">A configuração para a qual a execução ocorrerá. O padrão para a maioria dos projetos é 'Debug'.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ru.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ru.xlf
index b4405fe496f3..27eae3c03dc2 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ru.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.ru.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Не используйте launchSettings.json для настройки приложения.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Не используйте launchSettings.json для настройки приложения.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">При чтении launchSettings.json обнаружена ошибка.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ The default is to publish a framework-dependent application.</source>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Не удалось найти указанный профиль запуска "{0}".</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Your project targets multiple frameworks. Specify which framework to run using '
         <target state="translated">"{0}" не является допустимым файлом проекта.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Конфигурация для запуска. По умолчанию для большинства проектов используется "Debug".</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.tr.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.tr.xlf
index ee106fdb12e8..ff689e381c91 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.tr.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.tr.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">Uygulamayı yapılandırmak için launchSettings.json kullanmayı denemeyin.</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">Uygulamayı yapılandırmak için launchSettings.json kullanmayı denemeyin.</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">launchSettings.json okunurken bir hatayla karşılaşıldı.
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ Varsayılan durum, çerçeveye bağımlı bir uygulama yayımlamaktır.</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">Belirtilen başlatma profili '{0}' bulunamadı.</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Projeniz birden fazla Framework'ü hedefliyor. '{0}' kullanarak hangi Framework'
         <target state="translated">'{0}' geçerli bir proje dosyası değil.</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">Çalıştırılacak yapılandırma. Çoğu proje için varsayılan, ‘Hata Ayıklama’ seçeneğidir.</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hans.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hans.xlf
index f83cc0079bac..71e916b06251 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hans.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hans.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">请勿尝试使用 launchSettings.json 配置应用程序。</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">请勿尝试使用 launchSettings.json 配置应用程序。</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">读取 launchSettings.json 时发生错误。
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ The default is to publish a framework-dependent application.</source>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">找不到指定的启动配置文件“{0}”。</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Your project targets multiple frameworks. Specify which framework to run using '
         <target state="translated">“{0}”不是有效的项目文件。</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">要运行的配置。大多数项目的默认值是 "Debug"。</target>
diff --git a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hant.xlf b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hant.xlf
index 319cb3ae0d90..ef7727f48872 100644
--- a/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hant.xlf
+++ b/src/Cli/dotnet/Commands/xlf/CliCommandStrings.zh-Hant.xlf
@@ -956,9 +956,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="CommandOptionNoLaunchProfileDescription">
-        <source>Do not attempt to use launchSettings.json to configure the application.</source>
-        <target state="translated">請勿嘗試使用 launchSettings.json 設定該應用程式。</target>
-        <note />
+        <source>Do not attempt to use launchSettings.json or [app].run.json to configure the application.</source>
+        <target state="needs-review-translation">請勿嘗試使用 launchSettings.json 設定該應用程式。</target>
+        <note>{Locked="launchSettings.json"}{Locked=".run.json"}</note>
       </trans-unit>
       <trans-unit id="CommandOptionProjectDescription">
         <source>The path to the project file to run (defaults to the current directory if there is only one project).</source>
@@ -1081,11 +1081,9 @@ dotnet.config is a name don't translate.</note>
         <note />
       </trans-unit>
       <trans-unit id="DeserializationExceptionMessage">
-        <source>An error was encountered when reading launchSettings.json.
-{0}</source>
-        <target state="translated">讀取 launchSettings.json 時發生錯誤。
-{0}</target>
-        <note />
+        <source>An error was encountered when reading '{0}': {1}</source>
+        <target state="new">An error was encountered when reading '{0}': {1}</target>
+        <note>{0} is file path. {1} is exception message.</note>
       </trans-unit>
       <trans-unit id="DetailDescription">
         <source>Show detail result of the query.</source>
@@ -2626,8 +2624,10 @@ The default is to publish a framework-dependent application.</source>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionCouldNotLocateALaunchSettingsFile">
-        <source>The specified launch profile '{0}' could not be located.</source>
-        <target state="translated">找不到指定的啟動設定檔 '{0}'。</target>
+        <source>Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</source>
+        <target state="new">Cannot use launch profile '{0}' because the launch settings file could not be located. Locations tried:
+{1}</target>
         <note />
       </trans-unit>
       <trans-unit id="RunCommandExceptionMultipleProjects">
@@ -2668,6 +2668,11 @@ Your project targets multiple frameworks. Specify which framework to run using '
         <target state="translated">'{0}' 並非有效的專案名稱。</target>
         <note />
       </trans-unit>
+      <trans-unit id="RunCommandWarningRunJsonNotUsed">
+        <source>Warning: Settings from '{0}' are not used because '{1}' has precedence.</source>
+        <target state="new">Warning: Settings from '{0}' are not used because '{1}' has precedence.</target>
+        <note>{0} is an app.run.json file path. {1} is a launchSettings.json file path.</note>
+      </trans-unit>
       <trans-unit id="RunConfigurationOptionDescription">
         <source>The configuration to run for. The default for most projects is 'Debug'.</source>
         <target state="translated">要為其執行的組態。大部分的專案預設為「偵錯」。</target>
diff --git a/test/dotnet-watch.Tests/Process/LaunchSettingsProfileTest.cs b/test/dotnet-watch.Tests/Process/LaunchSettingsProfileTest.cs
index 44b57449f1c3..937cf6ddcf34 100644
--- a/test/dotnet-watch.Tests/Process/LaunchSettingsProfileTest.cs
+++ b/test/dotnet-watch.Tests/Process/LaunchSettingsProfileTest.cs
@@ -46,17 +46,17 @@ public void LoadsLaunchProfiles()
         }
         """);
 
-        var projectDirectory = Path.Combine(project.TestRoot, "Project1");
+        var projectPath = Path.Combine(project.TestRoot, "Project1", "Project1.csproj");
 
-        var expected = LaunchSettingsProfile.ReadLaunchProfile(projectDirectory, "http", _reporter);
+        var expected = LaunchSettingsProfile.ReadLaunchProfile(projectPath, launchProfileName: "http", _reporter);
         Assert.NotNull(expected);
         Assert.Equal("http://localhost:5000", expected.ApplicationUrl);
 
-        expected = LaunchSettingsProfile.ReadLaunchProfile(projectDirectory, "https", _reporter);
+        expected = LaunchSettingsProfile.ReadLaunchProfile(projectPath, "https", _reporter);
         Assert.NotNull(expected);
         Assert.Equal("https://localhost:5001", expected.ApplicationUrl);
 
-        expected = LaunchSettingsProfile.ReadLaunchProfile(projectDirectory, "notfound", _reporter);
+        expected = LaunchSettingsProfile.ReadLaunchProfile(projectPath, "notfound", _reporter);
         Assert.NotNull(expected);
     }
 
@@ -79,9 +79,9 @@ public void DefaultLaunchProfileWithoutProjectCommand()
         }
         """);
 
-        var projectDirectory = Path.Combine(project.TestRoot, "Project1");
+        var projectPath = Path.Combine(project.Path, "Project1", "Project1.csproj");
 
-        var expected = LaunchSettingsProfile.ReadLaunchProfile(projectDirectory, launchProfileName: null, _reporter);
+        var expected = LaunchSettingsProfile.ReadLaunchProfile(projectPath, launchProfileName: null, _reporter);
         Assert.Null(expected);
     }
 
diff --git a/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsCsProj.cs b/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsCsProj.cs
index 61c557fde2b3..06b7449494ac 100644
--- a/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsCsProj.cs
+++ b/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsCsProj.cs
@@ -375,19 +375,13 @@ public void ItGivesAnErrorWhenAttemptingToUseALaunchProfileThatDoesNotExistWhenT
                 .WithWorkingDirectory(testProjectDirectory)
                 .Execute("--launch-profile", "test");
 
-            string[] expectedErrorWords = CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile
-                .Replace("\'{0}\'", "")
-                .Split(" ")
-                .Where(word => !string.IsNullOrEmpty(word))
-                .ToArray();
-
             runResult
-                .Should()
-                .Pass()
-                .And
-                .HaveStdOutContaining("Hello World!");
-
-            expectedErrorWords.ForEach(word => runResult.Should().HaveStdErrContaining(word));
+                .Should().Pass()
+                .And.HaveStdOutContaining("Hello World!")
+                .And.HaveStdErrContaining(string.Format(CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile, "test", $"""
+                    {Path.Join(testInstance.Path, "Properties", "launchSettings.json")}
+                    {Path.Join(testInstance.Path, "MSBuildTestApp.run.json")}
+                    """));
         }
 
         [Fact]
diff --git a/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsVbProj.cs b/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsVbProj.cs
index 68c3a1ae210f..751e606b730e 100644
--- a/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsVbProj.cs
+++ b/test/dotnet.Tests/CommandTests/Run/GivenDotnetRunBuildsVbProj.cs
@@ -25,19 +25,13 @@ public void ItGivesAnErrorWhenAttemptingToUseALaunchProfileThatDoesNotExistWhenT
                 .WithWorkingDirectory(testProjectDirectory)
                 .Execute("--launch-profile", "test");
 
-            string[] expectedErrorWords = CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile
-                .Replace("\'{0}\'", "")
-                .Split(" ")
-                .Where(word => !string.IsNullOrEmpty(word))
-                .ToArray();
-
             runResult
-                .Should()
-                .Pass()
-                .And
-                .HaveStdOutContaining("Hello World!");
-
-            expectedErrorWords.ForEach(word => runResult.Should().HaveStdErrContaining(word));
+                .Should().Pass()
+                .And.HaveStdOutContaining("Hello World!")
+                .And.HaveStdErrContaining(string.Format(CliCommandStrings.RunCommandExceptionCouldNotLocateALaunchSettingsFile, "test", $"""
+                    {Path.Join(testInstance.Path, "My Project", "launchSettings.json")}
+                    {Path.Join(testInstance.Path, "VBTestApp.run.json")}
+                    """));
         }
 
         [Fact]
diff --git a/test/dotnet.Tests/CommandTests/Run/RunFileTests.cs b/test/dotnet.Tests/CommandTests/Run/RunFileTests.cs
index 5ceb6fe33f63..dbdb60002d6b 100644
--- a/test/dotnet.Tests/CommandTests/Run/RunFileTests.cs
+++ b/test/dotnet.Tests/CommandTests/Run/RunFileTests.cs
@@ -405,6 +405,15 @@ public void ReadFromStdin_NoBuild()
             .And.HaveStdErrContaining(string.Format(CliCommandStrings.InvalidOptionForStdin, RunCommandParser.NoBuildOption.Name));
     }
 
+    [Fact]
+    public void ReadFromStdin_LaunchProfile()
+    {
+        new DotnetCommand(Log, "run", "-", "--launch-profile=test")
+            .Execute()
+            .Should().Fail()
+            .And.HaveStdErrContaining(string.Format(CliCommandStrings.InvalidOptionForStdin, RunCommandParser.LaunchProfileOption.Name));
+    }
+
     /// <summary>
     /// <c>dotnet run -- -</c> should NOT read the C# file from stdin,
     /// the hyphen should be considred an app argument instead since it's after <c>--</c>.
@@ -1484,16 +1493,19 @@ public void ArtifactsDirectory_Permissions()
             .Should().Be(actualMode, artifactsDir);
     }
 
-    [Fact]
-    public void LaunchProfile()
+    [Theory]
+    [InlineData("Properties/launchSettings.json")]
+    [InlineData("Program.run.json")]
+    public void LaunchProfile(string relativePath)
     {
         var testInstance = _testAssetsManager.CreateTestDirectory();
         File.WriteAllText(Path.Join(testInstance.Path, "Program.cs"), s_program + """
 
             Console.WriteLine($"Message: '{Environment.GetEnvironmentVariable("Message")}'");
             """);
-        Directory.CreateDirectory(Path.Join(testInstance.Path, "Properties"));
-        File.WriteAllText(Path.Join(testInstance.Path, "Properties", "launchSettings.json"), s_launchSettings);
+        var fullPath = Path.Join(testInstance.Path, relativePath);
+        Directory.CreateDirectory(Path.GetDirectoryName(fullPath)!);
+        File.WriteAllText(fullPath, s_launchSettings);
 
         new DotnetCommand(Log, "run", "--no-launch-profile", "Program.cs")
             .WithWorkingDirectory(testInstance.Path)
@@ -1523,6 +1535,88 @@ Hello from Program
                 """);
     }
 
+    /// <summary>
+    /// <c>Properties/launchSettings.json</c> takes precedence over <c>Program.run.json</c>.
+    /// </summary>
+    [Fact]
+    public void LaunchProfile_Precedence()
+    {
+        var testInstance = _testAssetsManager.CreateTestDirectory();
+        File.WriteAllText(Path.Join(testInstance.Path, "Program.cs"), s_program + """
+
+            Console.WriteLine($"Message: '{Environment.GetEnvironmentVariable("Message")}'");
+            """);
+        Directory.CreateDirectory(Path.Join(testInstance.Path, "Properties"));
+        string launchSettings = Path.Join(testInstance.Path, "Properties", "launchSettings.json");
+        File.WriteAllText(launchSettings, s_launchSettings.Replace("TestProfileMessage", "PropertiesLaunchSettingsJson"));
+        string runJson = Path.Join(testInstance.Path, "Program.run.json");
+        File.WriteAllText(runJson, s_launchSettings.Replace("TestProfileMessage", "ProgramRunJson"));
+
+        new DotnetCommand(Log, "run", "--no-launch-profile", "Program.cs")
+            .WithWorkingDirectory(testInstance.Path)
+            .Execute()
+            .Should().Pass()
+            .And.HaveStdOut("""
+                Hello from Program
+                Message: ''
+                """);
+
+        new DotnetCommand(Log, "run", "Program.cs")
+            .WithWorkingDirectory(testInstance.Path)
+            .Execute()
+            .Should().Pass()
+            .And.HaveStdOut($"""
+                {string.Format(CliCommandStrings.RunCommandWarningRunJsonNotUsed, runJson, launchSettings)}
+                Hello from Program
+                Message: 'PropertiesLaunchSettingsJson1'
+                """);
+
+        new DotnetCommand(Log, "run", "-lp", "TestProfile2", "Program.cs")
+            .WithWorkingDirectory(testInstance.Path)
+            .Execute()
+            .Should().Pass()
+            .And.HaveStdOut($"""
+                {string.Format(CliCommandStrings.RunCommandWarningRunJsonNotUsed, runJson, launchSettings)}
+                Hello from Program
+                Message: 'PropertiesLaunchSettingsJson2'
+                """);
+    }
+
+    /// <summary>
+    /// Each file-based app in a folder can have separate launch profile.
+    /// </summary>
+    [Fact]
+    public void LaunchProfile_Multiple()
+    {
+        var testInstance = _testAssetsManager.CreateTestDirectory();
+        var source = s_program + """
+
+            Console.WriteLine($"Message: '{Environment.GetEnvironmentVariable("Message")}'");
+            """;
+        File.WriteAllText(Path.Join(testInstance.Path, "First.cs"), source);
+        File.WriteAllText(Path.Join(testInstance.Path, "First.run.json"), s_launchSettings.Replace("TestProfileMessage", "First"));
+        File.WriteAllText(Path.Join(testInstance.Path, "Second.cs"), source);
+        File.WriteAllText(Path.Join(testInstance.Path, "Second.run.json"), s_launchSettings.Replace("TestProfileMessage", "Second"));
+
+        new DotnetCommand(Log, "run", "First.cs")
+            .WithWorkingDirectory(testInstance.Path)
+            .Execute()
+            .Should().Pass()
+            .And.HaveStdOut("""
+                Hello from First
+                Message: 'First1'
+                """);
+
+        new DotnetCommand(Log, "run", "Second.cs")
+            .WithWorkingDirectory(testInstance.Path)
+            .Execute()
+            .Should().Pass()
+            .And.HaveStdOut("""
+                Hello from Second
+                Message: 'Second1'
+                """);
+    }
+
     [Fact]
     public void Define_01()
     {
diff --git a/test/dotnet.Tests/CommandTests/Test/GivenDotnetTestBuildsAndRunsTests.cs b/test/dotnet.Tests/CommandTests/Test/GivenDotnetTestBuildsAndRunsTests.cs
index 0387b25cf9a9..88f6626a9025 100644
--- a/test/dotnet.Tests/CommandTests/Test/GivenDotnetTestBuildsAndRunsTests.cs
+++ b/test/dotnet.Tests/CommandTests/Test/GivenDotnetTestBuildsAndRunsTests.cs
@@ -118,14 +118,18 @@ public void RunTestProjectWithTests_ShouldReturnExitCodeSuccess(string configura
             result.ExitCode.Should().Be(ExitCodes.Success);
         }
 
-        [InlineData(TestingConstants.Debug)]
-        [InlineData(TestingConstants.Release)]
-        [Theory]
-        public void RunTestProjectWithTestsAndLaunchSettings_ShouldReturnExitCodeSuccess(string configuration)
+        [Theory, CombinatorialData]
+        public void RunTestProjectWithTestsAndLaunchSettings_ShouldReturnExitCodeSuccess(
+            [CombinatorialValues(TestingConstants.Debug, TestingConstants.Release)] string configuration, bool runJson)
         {
             TestAsset testInstance = _testAssetsManager.CopyTestAsset("TestProjectWithLaunchSettings", Guid.NewGuid().ToString())
                 .WithSource();
 
+            if (runJson)
+            {
+                File.Move(Path.Join(testInstance.Path, "Properties", "launchSettings.json"), Path.Join(testInstance.Path, "TestProjectWithLaunchSettings.run.json"));
+            }
+
             CommandResult result = new DotnetTestCommand(Log, disableNewOutput: false)
                                     .WithWorkingDirectory(testInstance.Path)
                                     .Execute(TestingPlatformOptions.ConfigurationOption.Name, configuration);
diff --git a/test/dotnet.Tests/CompletionTests/snapshots/pwsh/DotnetCliSnapshotTests.VerifyCompletions.verified.ps1 b/test/dotnet.Tests/CompletionTests/snapshots/pwsh/DotnetCliSnapshotTests.VerifyCompletions.verified.ps1
index 5b7c6c8696f8..fffded025fed 100644
--- a/test/dotnet.Tests/CompletionTests/snapshots/pwsh/DotnetCliSnapshotTests.VerifyCompletions.verified.ps1
+++ b/test/dotnet.Tests/CompletionTests/snapshots/pwsh/DotnetCliSnapshotTests.VerifyCompletions.verified.ps1
@@ -830,7 +830,7 @@ Register-ArgumentCompleter -Native -CommandName 'testhost' -ScriptBlock {
                 [CompletionResult]::new('--file', '--file', [CompletionResultType]::ParameterName, "The path to the file-based app to run (can be also passed as the first argument if there is no project in the current directory).")
                 [CompletionResult]::new('--launch-profile', '--launch-profile', [CompletionResultType]::ParameterName, "The name of the launch profile (if any) to use when launching the application.")
                 [CompletionResult]::new('--launch-profile', '-lp', [CompletionResultType]::ParameterName, "The name of the launch profile (if any) to use when launching the application.")
-                [CompletionResult]::new('--no-launch-profile', '--no-launch-profile', [CompletionResultType]::ParameterName, "Do not attempt to use launchSettings.json to configure the application.")
+                [CompletionResult]::new('--no-launch-profile', '--no-launch-profile', [CompletionResultType]::ParameterName, "Do not attempt to use launchSettings.json or [app].run.json to configure the application.")
                 [CompletionResult]::new('--no-build', '--no-build', [CompletionResultType]::ParameterName, "Do not build the project before running. Implies --no-restore.")
                 [CompletionResult]::new('--interactive', '--interactive', [CompletionResultType]::ParameterName, "Allows the command to stop and wait for user input or action (for example to complete authentication).")
                 [CompletionResult]::new('--no-restore', '--no-restore', [CompletionResultType]::ParameterName, "Do not restore the project before building.")
diff --git a/test/dotnet.Tests/CompletionTests/snapshots/zsh/DotnetCliSnapshotTests.VerifyCompletions.verified.zsh b/test/dotnet.Tests/CompletionTests/snapshots/zsh/DotnetCliSnapshotTests.VerifyCompletions.verified.zsh
index a272700e55ab..21ed53e514ef 100644
--- a/test/dotnet.Tests/CompletionTests/snapshots/zsh/DotnetCliSnapshotTests.VerifyCompletions.verified.zsh
+++ b/test/dotnet.Tests/CompletionTests/snapshots/zsh/DotnetCliSnapshotTests.VerifyCompletions.verified.zsh
@@ -874,7 +874,7 @@ _testhost() {
                         '--file=[The path to the file-based app to run (can be also passed as the first argument if there is no project in the current directory).]:FILE_PATH: ' \
                         '--launch-profile=[The name of the launch profile (if any) to use when launching the application.]:LAUNCH_PROFILE: ' \
                         '-lp=[The name of the launch profile (if any) to use when launching the application.]:LAUNCH_PROFILE: ' \
-                        '--no-launch-profile[Do not attempt to use launchSettings.json to configure the application.]' \
+                        '--no-launch-profile[Do not attempt to use launchSettings.json or \[app\].run.json to configure the application.]' \
                         '--no-build[Do not build the project before running. Implies --no-restore.]' \
                         '--interactive=[Allows the command to stop and wait for user input or action (for example to complete authentication).]: :((False\:"False" True\:"True" ))' \
                         '--no-restore[Do not restore the project before building.]' \