diff --git a/src/tests/JIT/Regression/JitBlue/Runtime_101731/Runtime_101731.cs b/src/tests/JIT/Regression/JitBlue/Runtime_101731/Runtime_101731.cs
index 98c9f2a570ab76..ba409d336ebdf5 100644
--- a/src/tests/JIT/Regression/JitBlue/Runtime_101731/Runtime_101731.cs
+++ b/src/tests/JIT/Regression/JitBlue/Runtime_101731/Runtime_101731.cs
@@ -35,6 +35,7 @@ public static void TestConvertToInt64NativeDouble(double value)
 
     [Theory]
     [InlineData(float.MaxValue)]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void TestConvertToInt64NativeSingle(float value)
     {
         Func<float, long> func = float.ConvertToIntegerNative<long>;
@@ -44,6 +45,7 @@ public static void TestConvertToInt64NativeSingle(float value)
 
     [Theory]
     [InlineData(double.MaxValue)]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void TestConvertToUInt32NativeDouble(double value)
     {
         Func<double, uint> func = double.ConvertToIntegerNative<uint>;
@@ -53,6 +55,7 @@ public static void TestConvertToUInt32NativeDouble(double value)
 
     [Theory]
     [InlineData(float.MaxValue)]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void TestConvertToUInt32NativeSingle(float value)
     {
         Func<float, uint> func = float.ConvertToIntegerNative<uint>;
@@ -62,6 +65,7 @@ public static void TestConvertToUInt32NativeSingle(float value)
 
     [Theory]
     [InlineData(double.MaxValue)]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void TestConvertToUInt64NativeDouble(double value)
     {
         Func<double, ulong> func = double.ConvertToIntegerNative<ulong>;
@@ -71,6 +75,7 @@ public static void TestConvertToUInt64NativeDouble(double value)
 
     [Theory]
     [InlineData(float.MaxValue)]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void TestConvertToUInt64NativeSingle(float value)
     {
         Func<float, ulong> func = float.ConvertToIntegerNative<ulong>;
diff --git a/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayout.csproj b/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayout.csproj
index df524ba573d84c..4d379aec789420 100644
--- a/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayout.csproj
+++ b/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayout.csproj
@@ -4,7 +4,7 @@
 
     <!-- Tracking issue: https://github.com/dotnet/runtime/issues/119948 -->
     <MonoAotIncompatible>true</MonoAotIncompatible>
-    <DisableProjectBuild Condition="'$(RuntimeFlavor)' == 'mono'">true</DisableProjectBuild>
+    <DisableProjectBuild Condition="'$(RuntimeFlavor)' == 'mono' and '$(RuntimeVariant)' == 'minifullaot'">true</DisableProjectBuild>
   </PropertyGroup>
   <ItemGroup>
     <Compile Include="ExtendedLayout.cs" />
diff --git a/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayoutTypes.ilproj b/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayoutTypes.ilproj
index 3810a2df0cfd2e..21b020efb29e08 100644
--- a/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayoutTypes.ilproj
+++ b/src/tests/Loader/classloader/ExtendedLayout/ExtendedLayoutTypes.ilproj
@@ -1,6 +1,9 @@
 <Project Sdk="Microsoft.NET.Sdk.IL">
   <PropertyGroup>
     <OutputType>Library</OutputType>
+    <!-- Tracking issue: https://github.com/dotnet/runtime/issues/119948 -->
+    <MonoAotIncompatible>true</MonoAotIncompatible>
+    <DisableProjectBuild Condition="'$(RuntimeFlavor)' == 'mono' and '$(RuntimeVariant)' == 'minifullaot'">true</DisableProjectBuild>
   </PropertyGroup>
   <ItemGroup>
     <Compile Include="ExtendedLayoutTypes.il" />
diff --git a/src/tests/Loader/classloader/explicitlayout/objrefandnonobjrefoverlap/case13.cs b/src/tests/Loader/classloader/explicitlayout/objrefandnonobjrefoverlap/case13.cs
index b45e3a72d1e0d3..7df85a6ef6230c 100644
--- a/src/tests/Loader/classloader/explicitlayout/objrefandnonobjrefoverlap/case13.cs
+++ b/src/tests/Loader/classloader/explicitlayout/objrefandnonobjrefoverlap/case13.cs
@@ -155,6 +155,7 @@ public ref struct Explicit5b_Invalid64
     }
 
     [Fact]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/112557", TestRuntimes.Mono)]
     public static void Validate_Explicit5_Invalid()
     {
         if (Environment.Is64BitProcess)
diff --git a/src/tests/Regressions/coreclr/GitHub_76531/test76531.csproj b/src/tests/Regressions/coreclr/GitHub_76531/test76531.csproj
index ae1513d8e93546..9afaea7370e26a 100644
--- a/src/tests/Regressions/coreclr/GitHub_76531/test76531.csproj
+++ b/src/tests/Regressions/coreclr/GitHub_76531/test76531.csproj
@@ -5,6 +5,7 @@
     <!-- This test removes one of its dependencies at runtime, so it is not compatible with AOT  -->
     <MonoAotIncompatible>true</MonoAotIncompatible>
     <NativeAotIncompatible>true</NativeAotIncompatible>
+    <DisableProjectBuild Condition="'$(RuntimeFlavor)' == 'mono' and '$(RuntimeVariant)' == 'minifullaot'">true</DisableProjectBuild>
   </PropertyGroup>
   <ItemGroup>
     <Compile Include="test76531.cs" />