diff --git a/samtranslator/region_configuration.py b/samtranslator/region_configuration.py
index 2e6fa85b68..333ca3864f 100644
--- a/samtranslator/region_configuration.py
+++ b/samtranslator/region_configuration.py
@@ -18,7 +18,7 @@ def is_apigw_edge_configuration_supported(cls) -> bool:
         :return: True, if API Gateway does not support Edge configuration
         """
         partition = ArnGenerator.get_partition_name()
-        if partition.startswith("aws-iso") or partition in ["aws-us-gov", "aws-cn"]:
+        if partition.startswith("aws-iso") or partition in ["aws-us-gov", "aws-cn", "aws-eusc"]:
             return False
         return True
 
diff --git a/samtranslator/translator/arn_generator.py b/samtranslator/translator/arn_generator.py
index 5ab68e0821..3c67484917 100644
--- a/samtranslator/translator/arn_generator.py
+++ b/samtranslator/translator/arn_generator.py
@@ -24,6 +24,7 @@ def _region_to_partition(region: str) -> str:
         "us-gov": "aws-us-gov",
         "eu-isoe": "aws-iso-e",
         "us-isof": "aws-iso-f",
+        "eusc-": "aws-eusc",
     }
     for key, value in region_to_partition_map.items():
         if region_string.startswith(key):
diff --git a/tests/translator/test_arn_generator.py b/tests/translator/test_arn_generator.py
index 482d554010..f8428db717 100644
--- a/tests/translator/test_arn_generator.py
+++ b/tests/translator/test_arn_generator.py
@@ -18,6 +18,7 @@ def setUp(self):
             ("eu-isoe-west-1", "aws-iso-e"),
             ("US-EAST-1", "aws"),
             ("us-isof-east-1", "aws-iso-f"),
+            ("eusc-de-east-1", "aws-eusc"),
         ]
     )
     def test_get_partition_name(self, region, expected):
diff --git a/tests/unit/test_region_configuration.py b/tests/unit/test_region_configuration.py
index 9cbb10f665..6f5a661ebc 100644
--- a/tests/unit/test_region_configuration.py
+++ b/tests/unit/test_region_configuration.py
@@ -20,7 +20,9 @@ def test_when_apigw_edge_configuration_supported(self, partition):
 
             self.assertTrue(RegionConfiguration.is_apigw_edge_configuration_supported())
 
-    @parameterized.expand([["aws-cn"], ["aws-us-gov"], ["aws-iso"], ["aws-iso-b"], ["aws-iso-e"], ["aws-iso-f"]])
+    @parameterized.expand(
+        [["aws-cn"], ["aws-us-gov"], ["aws-iso"], ["aws-iso-b"], ["aws-iso-e"], ["aws-iso-f"], ["aws-eusc"]]
+    )
     def test_when_apigw_edge_configuration_is_not_supported(self, partition):
         with patch(
             "samtranslator.translator.arn_generator.ArnGenerator.get_partition_name"
diff --git a/tests/unit/translator/test_arn_generator.py b/tests/unit/translator/test_arn_generator.py
index f31cb7f26f..70faf83761 100644
--- a/tests/unit/translator/test_arn_generator.py
+++ b/tests/unit/translator/test_arn_generator.py
@@ -15,6 +15,7 @@ class TestArnGenerator(TestCase):
             ["us-iso-east-1", "aws-iso"],
             ["us-isob-east-1", "aws-iso-b"],
             ["eu-isoe-west-1", "aws-iso-e"],
+            ["eusc-de-east-1", "aws-eusc"],
         ]
     )
     def test_get_partition_name(self, region, expected_partition):