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T1w-dwiref co-registration refinement with brain masks #979

@pcamach2

Description

@pcamach2

Summary

The co-registration of ACPC space preprocessed T1w and dwiref images from QSIPrep (v1.0.1) appears to be significantly shifted along the inferior-superior axis for some of the 7 Tesla data collected at our site (see below)

Image Image

To address this offset, the brain masks for each respective image can be supplied to antsRegistration to prevent unwanted alignment of CSF/dura from the b0 image to skull in the T1w image. The images below are from the same dataset, after antsRegistration using the options specified in QSIPrep and the additional -x / --masks command-line argument.

coreg_masked.webm

Additional details

This additional masked registration was performed with existing outputs from QSIPrep.

Next steps

There are two options that could accomplish this end:

  1. Supply brain masks as an option in the co-registration step.
  2. Use a skull-stripped brain for the dwiref image to match the node input name ref_b0_brain.

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